Arnicolide C

Arnicolide C
Product Name Arnicolide C
CAS No.: 34532-67-7
Catalog No.: CFN91996
Molecular Formula: C19H26O5
Molecular Weight: 334.41 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Centipeda minima
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $398/5 mg
Arnicolide C exhibits significant antiallergy activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Biologically active constituents of Centipeda minima: Isolation of a new plenolin ester and the antiallergy activity of sesquiterpene lactones[Reference: WebLink]
    Two pseudoguianolide sesquiterpenes were isolated as antiallergic constituents of Centipeda minima, which has been used as a folk medicine in southeast Asia.
    METHODS AND RESULTS:
    One of the sesquiterpenes, 6-O-senesioylplenolin (2), is a new pseudoguaianolide sesquiterpene lactone, which was isolated along with known pseudoguaianolide, Arnicolide C (1). The two sesquiterpenes exhibited significant antiallergy activity in passive cutaneous anaphylaxis (PCA) tests. An amide isolated along with the sesquiterpenes was identified as aurantiamide acetate (3).
    CONCLUSIONS:
    Three flavonoids obtained from this plant also showed significant antiallergy activity.
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    METHODS AND RESULTS:
    The constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and HPLC-ODS, and identified by spectroscopic methods.Ten compounds, (-)-cis-chrysanthenol-O-beta-D-glucopyranoside (1), methy 3,5-dicaffeoylquinate (2), 3,5-di-O-caffeoyl quinicacid (3), tricin (4), 2-amino-4-methyl-pentanoicacid (5), 2-amino-3-phenyl-propionic acid (6), 4-amino-4-carboxychroman-2-one (7), brevilin-A (8), Arnicolide C (9), arnicolide D (10) were isolated and identified.
    CONCLUSIONS:
    Compounds 1-7 were isolated from the plant for the first time.
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