Tanshinlactone
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Two new abietane diterpenoids from Salvia yunnanensis.[Pubmed:
16450305]
METHODS AND RESULTS:
Two new abietane diterpenoids, yunnannin A ( 1) and danshenol C ( 2), were isolated from SALVIA YUNNANENSIS together with ten known diterpenoids, danshenol A ( 3), przewalskin ( 4), tanshinone IIA, tanshinone I, crypotanshinone, 1,2-dihydrotanshinone, Tanshinlactone, 5,6-dehydrosugiol, 12-hydroxy-6,7-seco-8,11,3-abietatriene-6,7-dial and phytol. Their structures were established based on spectroscopic data, chemical reactions and comparison with literature data. Compounds 1 - 3 were tested for their antitumor activity in T-24, QGY, K562, Me180 and BIU87 cell lines.
CONCLUSIONS:
Compound 3 showed inhibited growth of K562 (IC 50 = 0.53 μg/mL), T-24 (IC 50 = 7.94 μg/mL), QGY (IC 50 = 4.65 μg/mL) and Me180 (IC 50 = 6.89 μg/mL) cell lines while compound 2 was inactive. Compound 1 showed moderate inhibitory activity on QGY (IC 50 = 16.75 μg/mL) and Me180 (IC 50 = 5.84 μg/mL) cells.
