1,2-Dihydrotanshinquinone

1,2-Dihydrotanshinquinone
Product Name 1,2-Dihydrotanshinquinone
CAS No.: 77769-21-2
Catalog No.: CFN90333
Molecular Formula: C18H14O3
Molecular Weight: 278.3 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Red powder
Targets: Antifection
Source: The roots of Salvia miltiorrhiza Bge.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $413/5mg
1,2 Dihydrotanshinquinone is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Chem Biol Interact.2024, 395:110999.
  • Polytechnic University of Catalonia2017, 105826
  • Pharmaceuticals (Basel).2020, 13(10):302.
  • Oncol Lett.2020, 20(4):122.
  • Pharmacological Reports2020, 1-9
  • Nutrients.2020, 12(5):1242.
  • Onco Targets Ther.2017, 10:3467-3474
  • Cell.2022, 185(23):4298-4316.e21.
  • Front Cell Dev Biol.2021, 9:638174.
  • Tropical Journal of Pharmaceutical Research 2021, 20(6):1165-1170.
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