Soyasaponin Ac

Soyasaponin Ac
Product Name Soyasaponin Ac
CAS No.: 133882-74-3
Catalog No.: CFN90774
Molecular Formula: C67H104O32
Molecular Weight: 1421.6 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The seeds of Glycine max
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price:
Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Pharm Biomed Anal.2016, 129:50-59
  • Neurochem Res.2021, s11064-021-03449-0
  • Fitoterapia.2024, 177:106138.
  • Foods.2022, 11(6):882.
  • National Academy Science Letters2023, s40009.
  • FEBS Lett.2021, 595(20):2608-2615.
  • Microb Biotechnol.2021, 14(5):2009-2024.
  • Enzyme and Microbial Technology2022, 110002.
  • Food Sci Nutr.2023, 00:1-10.
  • Molecules.2019, 24(21):E3834
  • Soyasaponin Bd

    Catalog No: CFN90775
    CAS No: 135272-91-2
    Price: Inquiry(manager@chemfaces.com)
    Soyasaponin IV

    Catalog No: CFN93251
    CAS No: 108906-97-4
    Price: Inquiry(manager@chemfaces.com)
    Soyasaponin III

    Catalog No: CFN91596
    CAS No: 55304-02-4
    Price: Inquiry(manager@chemfaces.com)
    Soyasaponin II

    Catalog No: CFN93159
    CAS No: 55319-36-3
    Price: $318/5mg
    Soyasaponin Bb

    Catalog No: CFN90456
    CAS No: 51330-27-9
    Price: $138/20mg
    Soyasaponin Ba

    Catalog No: CFN90722
    CAS No: 114590-20-4
    Price: $418/20mg
    Soyasaponin Aa

    Catalog No: CFN90455
    CAS No: 117230-33-8
    Price: Inquiry(manager@chemfaces.com)
    Soyasaponin Ab

    Catalog No: CFN90773
    CAS No: 118194-13-1
    Price: Inquiry(manager@chemfaces.com)
    Soyasaponin Ac

    Catalog No: CFN90774
    CAS No: 133882-74-3
    Price: Inquiry(manager@chemfaces.com)
    Pedunsaponin C

    Catalog No: CFN80325
    CAS No: 272120-53-3
    Price: Inquiry(manager@chemfaces.com)
    Chinese Pharmacological Bulletin, 2018.
    Effect of soyasaponin on drug resistance of ovarian cancer cells.[Reference: WebLink]
    To screen the most effective soyasaponins for reversing the drug resistance of ovarian cancer cells,and investigate the possible mechanism.
    METHODS AND RESULTS:
    Cell viability assay was used to analyze the drug resistance of A2780/PTX cells treated with four different common soyasaponins respectively,in order to screen out the most effective soyasaponin. Then,the most effective soyasaponin was used to detect the expression of epithelial-mesenchymal transition (EMT)-related marker proteins, including N-cadherin and E-cadherin,with Western blot and confocal microscopy. Finally,transwell assay and wound healing assay were applied to observe effect of soyasaponin on regulating cancer cell migration. Compared with other soyasaponins,Soyasaponin Ac most effectively reversed the drug resistance of A2780/PTX cells. The expression of N-cadherin decreased while that of Ecadherin increased in A2780/PTX cells when treated with Soyasaponin Ac for 48 h. The results of transwell and wound healing assay suggested that Soyasaponin Ac also reduced the migration of A2780/PTX cells.
    CONCLUSIONS:
    Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells.
    Alloisoimperatorin

    Catalog No: CFN95012
    CAS No: 35214-83-6
    Price: $338/5mg
    Dactylorhin A

    Catalog No: CFN95032
    CAS No: 256459-34-4
    Price: $238/20mg
    Betmidin

    Catalog No: CFN95047
    CAS No: 35589-22-1
    Price: $413/5mg
    Gardenin D

    Catalog No: CFN95133
    CAS No: 29202-00-4
    Price: $318/5mg
    2-Methoxyfuranoguaia-9-ene-8-one

    Catalog No: CFN95220
    CAS No: 88010-62-2
    Price: $318/10mg
    Ginsenoside Rd2 (Quinquenoside L10)

    Catalog No: CFN95231
    CAS No: 83480-64-2
    Price: $318/10mg
    Secotubeimoside I

    Catalog No: CFN95347
    CAS No: 106235-32-9
    Price: $318/10mg
    10-O-trans-p-Feruloylscandoside

    Catalog No: CFN95392
    CAS No: 1428268-72-7
    Price: $318/10mg
    Cannabisin M

    Catalog No: CFN95436
    CAS No: 1831134-13-4
    Price: $318/5mg
    Ganolucidic acid D

    Catalog No: CFN95472
    CAS No: 102607-22-7
    Price: $413/5mg