Arjunglucoside I

Phytochemistry. 2010 Jan;71(1):95-9.

Saponins and a lignan derivative of Terminalia tropophylla from the Madagascar Dry Forest.[Pubmed: 19875137]

A study of an EtOH extract obtained from the roots of the Madagascan plant Terminalia tropophylla H. Perrier (Combretaceae) led to isolation of the oleanane-type triterpenoid saponin 1, the lignan derivative 2, and the two known saponins Arjunglucoside I (3) and sericoside (4).
METHODS AND RESULTS:
The structures of compounds 1 (terminaliaside A) and 2 (4'-O-cinnamoyl cleomiscosin A) were elucidated using 1D and 2D NMR experiments and mass spectrometry. Compound 1 showed antiproliferative activity against the A2780 human ovarian cancer cell line with an IC(50) value of 1.2 microM.

Phytochemistry Letters, 2008, 1(4):183-187.

Polyhydroxyoleanane-type triterpenoids from Combretum molle and their anti-inflammatory activity.[Reference: WebLink]

A new oleanane-type triterpene saponin, β-d-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (1), together with four known oleanane-type pentacyclic triterpenoids, combregenin (2), arjungenin (3), Arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle.
METHODS AND RESULTS:
Their structures were established mainly on the basis of 1D and 2D NMR spectral data. Compounds 1–3 exhibited more significant activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5.Graphical abstractThe new triterpene saponin, β-d-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (1) together with the known combregenin (2), arjungenin (3), Arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle.
CONCLUSIONS:
Their structures were identified by interpretation of their spectral data, mainly ESIMS, 1D NMR (1H, 13C NMR, DEPT) and 2D NMR (COSY, HSQC and HMBC), and by comparison with the literature. Compounds 1–3 exhibited more significant anti-inflammatory activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5.

Z Naturforsch C. 2017 May 1;72(5-6):203-208.

Termiglaucescin, a new polyhydroxy triterpene glucoside from Terminalia glaucescens with antioxidant and anti-inflammatory potential.[Pubmed: 27997356]

METHODS AND RESULTS:
Termiglaucescin (1), a new triterpene glucoside, has been isolated from the ethyl acetate extract of the root bark of Terminalia glaucescens Planch. ex Benth, together with 11 known compounds, β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (2), Arjunglucoside I (3), sericoside (4), arjungenin (5), sericic acid (6), arjunetin (7), chebuloside II (8), 3,3',4-tri-O-methylelagic acid (9), 3,3'-di-O-methylelagic acid (10), β-sitosterol (11) and stigmasterol (12). Compounds 2, 3, 7, 8 and 9 are reported from the plant for the first time.
CONCLUSIONS:
The structures of the isolated compounds were characterized by spectroscopic data interpretations, especially 1D and 2D NMR. The triterpenic isolates showed potent antioxidant and anti-inflammatory activities.