Rabdoserrin A

Rabdoserrin A
Product Name Rabdoserrin A
CAS No.: 96685-01-7
Catalog No.: CFN91931
Molecular Formula: C20H26O5
Molecular Weight: 346.42 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Rabdosia serra
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Appl Toxicol.2020, 40(7):965-978.
  • Biochem Biophys Res Commun.2020, 530(1):4-9.
  • Applied Biological Chemistry2020, 63:33(2020)
  • Biochem Pharmacol.2023, 211:115502.
  • Exp Ther Med.2019, 18(6):4388-4396
  • JPC-Journal of Planar Chromatography 2017, 30(2)
  • Pharmacol Res.2020, 161:105205.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2021, 1187:123012.
  • PLoS One.2018, 13(4):e0195642
  • Molecules.2023, 28(8):3291.
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    Antifungal activity and active ingredients of Rabdosia nervosa.[Reference: WebLink]

    METHODS AND RESULTS:
    The antifungal activity of methanol extract and active ingredients of Rabdosia nervosa were studied by using mycelial growth, column chromatography and spectral analysis. The results showed that the methanol extract presents the highest inhibitory activity against Phytophthora melonis, Peronophthora litchi and the active ingredients mainly concentrated in the chloroform extract. Six active ingredients were isolated: lasiokaurin, Rabdoserrin A, oridonin, nodosin, epinodosinol and enmein. The inhibitory rates against Phytophthora melonis of six active ingredients in 20 μg/mL were 54.61%, 42.73%, 75.50%, 59.84%, 51.11%, 24.13% respectively and 49.52%, 19.45%, 76.81%, 10.29%, 2.63%, 7.09% against Peronophthora litchi respectively, oridonin had the most remarkable antifungal activity.
    CONCLUSIONS:
    Oridonin could induce the mycelium over branch that was observed with optical microscope and its mechanism deserves further study.
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