R(+)-Gomisin M1

R(+)-Gomisin M1
Product Name R(+)-Gomisin M1
CAS No.: 82467-50-3
Catalog No.: CFN97309
Molecular Formula: C22H26O6
Molecular Weight: 386.4 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Targets: HIV
Source: The fruits of Schizandra chinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
(+/-)-Gomisin M1 exhibits potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Chinese Medicine2019, 14(1)
  • Evid Based Complement Alternat Med.2020, 2020:9416962.
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • J Ethnopharmacol.2017, 198:87-90
  • Biomolecules2021, 11(10),1513.
  • Applied Biological Chemistry2023, 66(58):112.
  • Medicina (Kaunas).2020, 56(12):685.
  • Life Sci.2022, 298:120488.
  • Biomed Pharmacother.2021, 139:111585.
  • Pharmaceuticals (Basel).2024, 17(1):108.
  • Gomisin N

    Catalog No: CFN90125
    CAS No: 69176-52-9
    Price: $218/20mg
    Schizandrin B

    Catalog No: CFN99923
    CAS No: 61281-37-6
    Price: $50/20mg
    Gomisin A

    Catalog No: CFN98990
    CAS No: 58546-54-6
    Price: $60/20mg
    R(+)-Gomisin M1

    Catalog No: CFN97309
    CAS No: 82467-50-3
    Price: Inquiry(manager@chemfaces.com)
    Schisanhenol

    Catalog No: CFN90364
    CAS No: 69363-14-0
    Price: $80/20mg
    Gomisin K1

    Catalog No: CFN96724
    CAS No: 75629-20-8
    Price: Inquiry(manager@chemfaces.com)
    Gomisin M2

    Catalog No: CFN97306
    CAS No: 82425-45-4
    Price: Inquiry(manager@chemfaces.com)
    Gomisin L1

    Catalog No: CFN96734
    CAS No: 82425-43-2
    Price: Inquiry(manager@chemfaces.com)
    Gomisin L2

    Catalog No: CFN96726
    CAS No: 82425-44-3
    Price: Inquiry(manager@chemfaces.com)
    Isokadsuranin

    Catalog No: CFN90912
    CAS No: 82467-52-5
    Price: $333/5mg
    J Nat Prod. 2006 Dec;69(12):1697-701.
    Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora.[Pubmed: 17190445 ]

    METHODS AND RESULTS:
    Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (R(+)-Gomisin M1,4), (+)-gomisin M2 (5), schisanhenol (6), deoxyschisandrin, schisantherin B, schisandrin, tigloylgomisin P, gomisin O, angeloylgomisin P, and epigomisin O. Their structure and stereochemistry were determined by spectroscopic methods, including 2D-NMR techniques. Compounds 1 and 3-6 were active as anti-HIV agents.
    CONCLUSIONS:
    (+/-)-Gomisin M1 (R(+)-Gomisin M1,4) exhibited the most potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively.
    Planta Med 1984; 50(5): 414-417
    Studies on the Chemical Constituents of Kadsura longipedunculata: Isolation and Structure Elucidation of Five New Lignans[Reference: WebLink]

    METHODS AND RESULTS:
    Five new dibenzocyclooctadiene lignans, R(+)-wuweizisu C (1), kadsuranin (2), R(+)-Gomisin M1 (3), R(+)-angeloylgomisin M1 (4) and angeloylgomisin R (5) were isolated from the ethereal extract of roots and stems of Kadsura longipedunculata Finet et Gagnep.
    CONCLUSIONS:
    Their structures were elucidated on the basis of chemical and spectral analysis.
    Lonicerin

    Catalog No: CFN95055
    CAS No: 25694-72-8
    Price: $168/10mg
    Lucidumol A

    Catalog No: CFN95059
    CAS No: 217476-73-8
    Price: $318/5mg
    2''-O-acetylsaikosaponin A

    Catalog No: CFN95085
    CAS No: 102934-42-9
    Price: $318/5mg
    5-Hydroxy-1-(4-hydroxyphenyl)-7-phenyl-3-heptanone (AO 2210)

    Catalog No: CFN95137
    CAS No: 105955-04-2
    Price: $318/10mg
    7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one

    Catalog No: CFN95140
    CAS No: 100667-52-5
    Price: $318/5mg
    Eriodictyol 7-O-glucuronide

    Catalog No: CFN95290
    CAS No: 125535-06-0
    Price: $318/10mg
    New compound 10

    Catalog No: CFN95343
    CAS No: N/A
    Price: $318/5mg
    Benzylpropyl acetate

    Catalog No: CFN95495
    CAS No: 7492-40-2
    Price: $318/5mg
    Ganolucidic acid E

    Catalog No: CFN95536
    CAS No: 114567-50-9
    Price: $318/5mg
    Clinopodic acid E

    Catalog No: CFN95595
    CAS No: 159736-38-6
    Price: $318/5mg