Pinoresinol 4-O-beta-D-glucopyranoside

Pinoresinol 4-O-beta-D-glucopyranoside
Product Name Pinoresinol 4-O-beta-D-glucopyranoside
CAS No.: 69251-96-3
Catalog No.: CFN97180
Molecular Formula: C26H32O11
Molecular Weight: 520.5 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The rhizomes of Polygonatum sibiricum Red.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $298/20mg
(+)-Pinoresinol 4-O-beta-D-glucopyranoside revealed that the presence of a vanilloyl group in the sugar moiety of (+)-pinoresinol 4-O-[6″-O-vanilloyl]-β-D-glucopyranoside is crucial for its anti-influenza virus activity.
Inquire / Order:
Technical Inquiries:
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to:

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • Nat Chem Biol.2018, 14(8):760-763
  • Inflammation.2015, 38(4):1502-16
  • Antioxidants (Basel).2019, 8(8):E307
  • Cancer Manag Res.2019, 11:483-500
  • J Hematol Oncol.2018, 11(1):112
  • Oncol Rep.2019, 41(4):2453-2463
  • J of Physics Conference Series2019, 1349(1)
  • Journal of Life Science2018, 917-922
  • Front Immunol.2017, 8:1542
  • Pinoresinol 4-O-beta-D-glucopyranoside

    Catalog No: CFN97180
    CAS No: 69251-96-3
    Price: $298/20mg

    Catalog No: CFN80044
    CAS No: 24404-49-7
    Price: Inquiry(
    Pinoresinol diglucoside

    Catalog No: CFN99994
    CAS No: 63902-38-5
    Price: $100/20mg
    8-Hydroxypinoresinol diglucoside

    Catalog No: CFN95083
    CAS No: 112747-99-6
    Price: $318/5mg

    Catalog No: CFN92432
    CAS No: 81426-17-7
    Price: Inquiry(

    Catalog No: CFN00449
    CAS No: 81426-14-4
    Price: Inquiry(

    Catalog No: CFN90676
    CAS No: 951677-22-8
    Price: $368/5mg

    Catalog No: CFN96416
    CAS No: 13060-14-5
    Price: $398/5mg

    Catalog No: CFN96723
    CAS No: 24192-64-1
    Price: Inquiry(
    Pinoresinol dimethyl ether

    Catalog No: CFN90879
    CAS No: 29106-36-3
    Price: $238/10mg
    PLoS One. 2014 Aug 7;9(8):e104544.
    In vitro anti-influenza virus activities of a new lignan glycoside from the latex of Calotropis gigantea.[Pubmed: 25102000]
    A new lignan glycoside, (+)-pinoresinol 4-O-[6″-O-vanilloyl]-β-D-glucopyranoside (1) and two known phenolic compounds, 6'-O-vanilloyltachioside (2) and 6'-O-vanilloylisotachioside (3) were isolated from the latex of Calotropis gigantea (Asclepiadaceae).
    The structure of the new compound was elucidated by using spectroscopic and chemical methods. Three isolates (1-3) and one authentic compound, (+)- Pinoresinol 4-O-beta-D-glucopyranoside, were screened for A/PR/8/34 (H1N1) inhibitory activity by cytopathic effect (CPE) inhibition assay on MDCK cells. Compound 1 showed inhibitory activity against A/PR/8/34 (H1N1). In sharp contrast, the other three compounds (2, 3 and (+)-Pinoresinol 4-O-beta-D-glucopyranoside) did not show such activity. An analysis of structure-activity relationship between 1 and (+)-Pinoresinol 4-O-beta-D-glucopyranoside revealed that the presence of a vanilloyl group in the sugar moiety of 1 is crucial for its anti-influenza virus activity. Compound 1 was further evaluated for in vitro inhibitory activities against a panel of human and avian influenza viruses by CPE inhibition assay. It showed inhibitory effect against human influenza viruses in both subtypes A and B (IC50 values around 13.4-39.8 µM with SI values of 3.7-11.4), while had no effect on avian influenza viruses. Its antiviral activity against human influenza viruses subtype A was further confirmed by plaque reduction assay. The time course assay indicated that 1 exerts its antiviral activity at the early stage of viral replication. A mechanistic study showed that 1 efficiently inhibited influenza virus-induced activation of NF-κB pathway in a dose-dependent manner, but had no effect on virus-induced activation of Raf/MEK/ERK pathway. Further studies demonstrated that nuclear translocation of transcription factor NF-κB induced by influenza virus was significantly blocked by 1, meanwhile, nuclear export of viral ribonucleoproteins was also effectively inhibited.
    These findings suggest that this new lignan glycoside from Calotropis gigantea, may have therapeutic potential in influenza virus infection through inhibition of NF-κB pathway and viral ribonucleoproteins nuclear export.

    Catalog No: CFN99295
    CAS No: 118916-57-7
    Price: $388/5mg
    (-)-Catechin gallate(CG)

    Catalog No: CFN98504
    CAS No: 130405-40-2
    Price: $348/20mg

    Catalog No: CFN96098
    CAS No: 87562-14-9
    Price: $333/5mg

    Catalog No: CFN90742
    CAS No: 510-77-0
    Price: $318/10mg
    3,5-Di-O-caffeoylquinic acid methyl ester

    Catalog No: CFN90857
    CAS No: 159934-13-1
    Price: $388/5mg

    Catalog No: CFN95031
    CAS No: 449172-61-6
    Price: $413/5mg
    Shancigusin I

    Catalog No: CFN95061
    CAS No: 1435488-35-9
    Price: $388/5mg

    Catalog No: CFN95063
    CAS No: 161099-37-2
    Price: $333/5mg
    Bryonamide A

    Catalog No: CFN91056
    CAS No: 75268-14-3
    Price: $268/5mg
    Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside

    Catalog No: CFN95109
    CAS No: 868557-54-4
    Price: $338/5mg