Pilloin | CAS:32174-62-2 | Manufacturer ChemFaces

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Nutrients.2019, 12(1)

The Journal of Agromedicine and Medical Sciences2018, 4(1)

Microchemical Journal2018, 137:168-173

Int J Mol Sci.2023, 24(24):17589.

Phytomedicine.2024, 125:155350.

Environ Toxicol.2022, 37(3):514-526.

Antioxidants (Basel).2023, 12(7):1324.

BMC Complement Altern Med.2014, 14:242

Separations2021, 8(7),90.

Pharmacol Rep.2020, 72(2):472-480.

Pharmaceutical Biology, 2008, 40(4):245-248.

Effects of the Flavonoid Pilloin Isolated from Marrubium cylleneum on Mitogen-Induced Lymphocyte Transformation[Reference: WebLink]

Flavonoids are known to exhibit a wide range of biological functions.
METHODS AND RESULTS:
In the present study, the possible immunomodulatory and cytotoxic effects of Pilloin, a flavone extracted from the Greek endemic herb Marrubium cylleneum were investigated by using the in vitro lymphocyte transformation and the cytotoxicity assays, respectively. Apigenin was used as the control flavonoid.
CONCLUSIONS:
Pilloin exerted a cytotoxic action targeted at the transformed lymphoblasts. On the other hand, the glycosylated flavonoid chrysoeriol-7- O -ß-D-(3β- E-p -coumaroyl)-glucopyranoside was inactive, providing further evidence that glycosylation may eliminate the effects of aglycones.

Product Name	Pilloin
CAS No.:	32174-62-2
Catalog No.:	CFN96503
Molecular Formula:	C₁₇H₁₄O₆
Molecular Weight:	314.29 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Marrubium cylleneum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$218/10mg