Pilloin
Pilloin exerts a cytotoxic action targeted at the transformed lymphoblasts.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Food Control2022, 132:108434.
Journal of functional foods2018, 171-182
Oncotarget.2017, 8(64):108006-108019
Molecules.2020, 25(18):4283.
Plants (Basel).2021, 10(11):2317.
Tissue Cell.2024, 88:102401.
Forensic Sci Int.2022, 341:111475.
J Appl Biol Chem.2024, V67:46-53
Foods.2022, 11(12):1708.
Pharmaceuticals.2022, 15(4), 402.
Related and Featured Products
Eupatilin
Catalog No: CFN90190
CAS No: 22368-21-4
Price: $68/20mg
5-Demethylsinensetin
Catalog No: CFN95415
CAS No: 21763-80-4
Price: $318/10mg
Sinensetin
Catalog No: CFN99599
CAS No: 2306-27-6
Price: $100/20mg
Isosinensetin
Catalog No: CFN90806
CAS No: 17290-70-9
Price: $218/20mg
5-O-Demethylnobiletin
Catalog No: CFN90921
CAS No: 2174-59-6
Price: $118/20mg
Nobiletin
Catalog No: CFN98726
CAS No: 478-01-3
Price: $30/20mg
3,5,6,7,8,4'-hexamethoxyflavone
Catalog No: CFN91805
CAS No: 34170-18-8
Price: Inquiry(manager@chemfaces.com)
3,3',4',5,6,7,8-heptamethoxyflavone
Catalog No: CFN95021
CAS No: 1178-24-1
Price: $268/10mg
4'-Hydroxyflavone
Catalog No: CFN91544
CAS No: 4143-63-9
Price: $30/20mg
4'-Methoxyflavone
Catalog No: CFN70361
CAS No: 4143-74-2
Price: Inquiry(manager@chemfaces.com)
Pharmaceutical Biology, 2008, 40(4):245-248.
Effects of the Flavonoid Pilloin Isolated from Marrubium cylleneum on Mitogen-Induced Lymphocyte Transformation[Reference:
WebLink]
Flavonoids are known to exhibit a wide range of biological functions.
METHODS AND RESULTS:
In the present study, the possible immunomodulatory and cytotoxic effects of Pilloin, a flavone extracted from the Greek endemic herb Marrubium cylleneum were investigated by using the in vitro lymphocyte transformation and the cytotoxicity assays, respectively. Apigenin was used as the control flavonoid.
CONCLUSIONS:
Pilloin exerted a cytotoxic action targeted at the transformed lymphoblasts. On the other hand, the glycosylated flavonoid chrysoeriol-7- O -ß-D-(3β- E-p -coumaroyl)-glucopyranoside was inactive, providing further evidence that glycosylation may eliminate the effects of aglycones.
