Otophylloside F

Otophylloside F
Product Name Otophylloside F
CAS No.: 250217-73-3
Catalog No.: CFN89258
Molecular Formula: C48H76O16
Molecular Weight: 909.11 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The roots of Cynanchum otophyllum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Otophylloside F can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Front Plant Sci.2018, 9:1424
  • J Korean Soc Food Sci Nutr2023, 52(12):1248-1255
  • Chem Biodivers.2023, 20(12):e202301461.
  • J Microbiol Biotechnol.2022, 32(2):141-148.
  • Sains Malaysiana2024, 53(2):397-408.
  • Fitoterapia.2024, 175:105958.
  • J Cell Biochem.2024, 125(4):e30537.
  • Phytochem Anal.2016, 27(5):296-303
  • Anticancer Agents Med Chem.2023, 23(10):1204-1210.
  • Biochem Biophys Res Commun.2020, 530(1):4-9.
  • Dregeoside A11

    Catalog No: CFN96087
    CAS No: 89020-11-1
    Price: Inquiry(manager@chemfaces.com)
    Otophylloside B 4'''-O-alpha-L-cymaropyranoside

    Catalog No: CFN89225
    CAS No: 171422-82-5
    Price: Inquiry(manager@chemfaces.com)
    Otophylloside B 4'''-O-beta-D-cymaropyranoside

    Catalog No: CFN89237
    CAS No: 171422-85-8
    Price: Inquiry(manager@chemfaces.com)
    Otophylloside B 4'''-O-beta-D-oleandropyranoside

    Catalog No: CFN89226
    CAS No: 168001-54-5
    Price: Inquiry(manager@chemfaces.com)
    Otophylloside O

    Catalog No: CFN89036
    CAS No: 1326583-08-7
    Price: Inquiry(manager@chemfaces.com)
    Cynatratoside A

    Catalog No: CFN96784
    CAS No: 97399-96-7
    Price: Inquiry(manager@chemfaces.com)
    Glaucogenin C mono-D-thevetoside

    Catalog No: CFN96787
    CAS No: 849201-84-9
    Price: Inquiry(manager@chemfaces.com)
    Glaucoside A

    Catalog No: CFN95299
    CAS No: 81474-91-1
    Price: $318/5mg
    Glaucoside C

    Catalog No: CFN95300
    CAS No: 81474-89-7
    Price: $318/5mg
    Cynanoside F

    Catalog No: CFN91815
    CAS No: 1800029-50-8
    Price: Inquiry(manager@chemfaces.com)
    J Nat Prod. 2015 Jul 24;78(7):1548-55.
    Bioactive C21 Steroidal Glycosides from the Roots of Cynanchum otophyllum That Suppress the Seizure-like Locomotor Activity of Zebrafish Caused by Pentylenetetrazole.[Pubmed: 26135914]

    METHODS AND RESULTS:
    Six new C21 steroidal glycosides, cynotophyllosides A-F (1-6), together with 16 known compounds, were isolated from the roots of Cynanchum otophyllum. The structures of the new compounds were elucidated by spectroscopic analysis and chemical methods. The three major components, Otophylloside F (15), otophylloside B (17), and rostratamine 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside (18), suppressed the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.
    CONCLUSIONS:
    Preliminary structure-activity relation studies revealed that a pregnene skeleton with a C-12 ester group (ikemaoyl > cinnamoyl > hydroxy > p-hydroxybenzoyl) and a C-3 sugar chain consisting of three 2,6-dideoxysaccharide units is essential for this suppressive activity.
    Pd-C-II

    Catalog No: CFN95003
    CAS No: N/A
    Price: $358/5mg
    20-O-Glucoginsenoside Rf

    Catalog No: CFN95036
    CAS No: 68406-27-9
    Price: $318/5mg
    Polygalasaponin XLIX

    Catalog No: CFN95117
    CAS No: 1033593-12-2
    Price: $318/10mg
    Silychristin B

    Catalog No: CFN95160
    CAS No: 879325-58-3
    Price: $318/5mg
    Momordicine V

    Catalog No: CFN95164
    CAS No: 1012315-36-4
    Price: $463/5mg
    Astin A

    Catalog No: CFN95187
    CAS No: 151201-75-1
    Price: $318/10mg
    [(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one

    Catalog No: CFN95198
    CAS No: 75412-95-2
    Price: $318/10mg
    Sibiricose A4

    Catalog No: CFN95298
    CAS No: 241125-73-5
    Price: $318/5mg
    Kaempferol 3,4'-di-O-glucoside

    Catalog No: CFN95357
    CAS No: 71939-16-7
    Price: $318/5mg
    Gardoside methyl ester

    Catalog No: CFN95467
    CAS No: 93930-20-2
    Price: $318/10mg