Tenacissoside F
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Sci Rep.2019, 9:12132
Molecules.2016, 21(6)
J Agric Food Chem.2021, 69(46):14037-14047.
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Molecules.2023, 28(7):3039.
Hindawi J of Food Biochemistry2023, P17:8883860
Eur J Pharm Sci.2016, 94:33-45
Drug Dev Res.2020, doi: 10.1002
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Biomed Chromatogr. 2014 Feb;28(2):223-30.
Simultaneous determination of six C21 steroids of Xiao-Ai-Ping injection in rat plasma by LC-MS/MS.[Pubmed:
24037806]
METHODS AND RESULTS:
A sensitive and specific liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed and validated the first time for simultanenous determination of three isomeric pregnane genins (17β-tenacigenin B, tenacigenin B and tenacigenin A) and their corresponding glycosides (tenacigenoside A, Tenacissoside F and marsdenoside I) from XAPI in rat plasma. The method showed satisfactory linearity over a concentration range 5.00-2000.00 ng/mL for tenacigenin B, tenacigenin A, marsdenoside I and Tenacissoside F (r(2) > 0.99), 10.00-4000.00 ng/mL for 17β-tenacigenin B and tenacigenoside A (r(2) > 0.99). Intra- and inter-day precisions (valued as relative standard deviation) were <9.00% and accuracies (as relative error) in the range -6.31 to 7.23%.
CONCLUSIONS:
Finally, this validated method was successfully applied to the pharmacokinetic study of XAPI after intravenous administration to rats.
