Glaucogenin C mono-D-thevetoside
Glaucogenin C mono-D-thevetoside is a natural product from Cynanchum stauntonii.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Heliyon.2023, 9:e21652.
National University of Pharmacy2022, 1:73-76
Oncol Rep.2021, 46(2):166.
LWT2024, 200:116184.
Sains Malaysiana2024, 53(2):397-408.
Am J Chin Med.2023, 51(4):1019-1039.
Planta Med.2019, 85(3):217-224
Clin Transl Med.2021, 11(5):e392.
Pharmaceuticals (Basel).2022, 15(8):982.
Food Science and Biotechnology2022, 10.1007.
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Planta Med. 2004 Nov;70(11):1075-9.
Steroids from the roots of Cynanchum stauntonii.[Pubmed:
15549665 ]
METHODS AND RESULTS:
A chemical investigation of the roots of Cynanchum stauntonii has resulted in the characterization of a new hydroperoxide with a 13,14 : 14,15-disecopregnane-type skeleton, named stauntonine (1), together with three related compounds, anhydrohirundigenin (2), anhydrohirundigenin monothevetoside (3), and Glaucogenin C mono-D-thevetoside(4). Their structures were established by spectroscopic methods, including X-ray crystallographic diffraction analysis of stauntonine that confirmed its relative stereochemistry.
CONCLUSIONS:
The compound 1 showed dose-dependent relaxation on aortic rings with endothelium contracted by phenylepherine or KCl.
