Neonuezhenide
Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Chem Pharm Bull (Tokyo). 2001 Jun;49(6):780-4.
Antioxidative glucosides from the fruits of Ligustrum lucidum.[Pubmed:
11411539]
.
METHODS AND RESULTS:
The ethanol extract of the fruits of Ligustrum lucidum was shown to have inhibitory effects on the hemolysis of red blood cells induced by 2,2'-azo-bis-(2-amidinopropane) dihydrochloride. Bioassay-guided analysis led to the isolation of ten secoiridoid glucosides. Two of them were new, lucidumosides C and D. Their structures were elucidated by spectroscopic methods. The other eight compounds were identified as oleoside dimethyl ester, ligustroside, oleuropein, nuezhenide, isonuezhenide, Neonuezhenide, lucidumoside A and lucidumoside B.
CONCLUSIONS:
Five compounds, oleoside dimethyl ester, oleuropein, Neonuezhenide, lucidumoside B and lucidumoside C, exhibited strong antioxidant effect against hemolysis of red blood cells induced by free radicals.
Chem Pharm Bull (Tokyo). 2016;64(1):73-7.
New Iridoid Glycosides with Antidepressant Activity Isolated from Cyperus rotundus.[Pubmed:
26726748]
METHODS AND RESULTS:
Based on bioactive screening results, two new iridoid glycosides, named rotunduside G (1) and rotunduside H (2), were isolated from the rhizomes of Cyperus rotundus, together with four known ones, negundoside (3), nishindaside (4), isooleuropein (5) and Neonuezhenide (6). Their structures were elucidated on the basis of spectroscopic methods and from literature values.
CONCLUSIONS:
In mice models of despair, 1 and 2 showed significant antidepressant activity.
