Momordicoside K
Momordicoside K has antidiabetic activity.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Toxicol Mech Methods.2021, 1-12.
Drug Invention Today2019, 12(6):1303-1306
African J. Agricultural Research 2017, 12(13):1164-1168
Faculty of Chem. & Nat. Resource Eng.2014, 62
Chinese Journal of Tissue Engineering Research2024, 28(8):1149-1154.
Molecules.2015, 20(10):19172-88
J Pharmacol Sci.2021, 147(2):184-191.
Eur J Pharmacol.2018, 832:96-103
Food Sci Biotechnol.2024, 33(15):3629-3637.
Journal of Food Hygiene and Safety2019, 34(5):413-420
Related and Featured Products
Nat Prod Commun. 2014 Jun;9(6):765-9.
Novel cucurbitane triterpenoids and anti-cholinesterase activities of constituents from Momordica charantia L.[Pubmed:
25115074]
METHODS AND RESULTS:
The C-19 epimers of 5beta,19-epoxycucurbita-6,23(E),25(26)-triene-3f,19-diol (1) and 5/,19-epoxy-25-methoxycucurbita-6,23-diene-3beta,19-diol (2) along with (19R,23E)-5beta,19-epoxy-19-methoxycucurbita-6,23,25-trien-3beta-ol (3), (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (4), ligballinol (5), charantin (6) and Momordicoside K(7) were isolated from the green fruits of Momordica charantia. The (S)-epimers of 1 and 2 are the first reports in nature.
CONCLUSIONS:
The acetyl- and butyryl-cholinesterase inhibitory activities of the isolated compounds were evaluated, and 5 showed the highest activity of these compounds against butyrylcholinesterase (IC50 = 32.20 microM) with a reversible and non-competitive inhibition mode.
