Galangin 3-methyl ether
Galangin-3-methylether has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. 3-Methylethergalangin has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytomedicine. 2003;10(6-7):490-3.
Trypanocidal activity of Lychnophora staavioides Mart. (Vernonieae, Asteraceae).[Pubmed:
13678232]
METHODS AND RESULTS:
In the continuing search for new compounds with trypanocidal activity for use in blood banks to prevent the transmission of Chagas' disease, a trypanocidal extract of Lychnophora staavioides Mart. (Vernonieae, Asteraceae) was fractionated using several chromatographic techniques and afforded the following flavonoids: tectochrysin, pinostrobin, pinobanksin, pinobanksin 3-acetate, pinocembrin, chrysin, Galangin 3-methyl ether, quercetin 3-methyl ether, chrysoeriol and vicenin-2.
CONCLUSIONS:
The most active compound was quercetin 3-methyl ether, which showed no blood lysis activity and which represents a promising compound for use against T. cruzi in blood banks.
Z Naturforsch C. 2009 Jul-Aug;64(7-8):509-12.
Bioactivity of flavonoids isolated from Lychnophora markgravii against Leishmania amazonensis amastigotes.[Pubmed:
19791501]
METHODS AND RESULTS:
The bioactivity of the flavonoids pinostrobin (1), pinocembrin (2), tectochrysin (3), Galangin 3-methyl ether (4), and tiliroside (5) isolated from Lychnophora markgravii aerial parts was investigated in vitro against amastigote stages of Leishmania amazonensis. The compounds were isolated by several chromatographic techniques and their chemical structures were established by ESI-MS and NMR spectroscopic data.
CONCLUSIONS:
The flavonoids 1 and 3 were the most active compounds; they markedly reduced the viability of Leishmania amastigotes.
