Notoptol

Notoptol
Product Name Notoptol
CAS No.: 88206-49-9
Catalog No.: CFN95218
Molecular Formula: C21H22O5
Molecular Weight: 354.4 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The roots of Notopterygium incisum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/5mg
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Nat Prod Sci.2014, 20(3):182-190
  • Int J Mol Sci.2021, 22(10):5181.
  • Tissue Cell.2022, 78:101901.
  • JLiquid Chromatography & Related Tech.2021, 10826076.
  • Molecules.2020 ,25(16):3697.
  • Food Chem.2019, 274:345-350
  • Environ Toxicol.2019, 34(12):1354-1362
  • Integr Cancer Ther.2018, 17(3):832-843
  • Oxid Med Cell Longev.2022, 2022:5888636.
  • Trop J Pharm Res.2023, 22(3):283-288.
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    Zhongguo Zhong Yao Za Zhi. 2008 Dec;33(24):2918-21.
    Studies on chemical constituents in roots and rhizomes of Notopterygium incisum.[Pubmed: 19294850]
    To study the chemical constituents in the roots and rhizomes of Notopterygium incisum.
    METHODS AND RESULTS:
    The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences. Twenty-four compounds were obtained and identified as isocalamenediol (1), pregnenolone (2), beta-sitosterol (3), bergapten (4), bergaptol (5), cnidilin (6), isoimperatorin (7), bergamottin (8), demethylfuropinnarin (9), nodakenetin (10), 7'-O-methylNotoptol (11), notopterol (12), Notoptol (13), pabulenol (14), phenethylferulate (15), p-hydroxyphenethyl anisate (16), trans-ferulic acid (17), nodakenin (18), sucrose (19), 2-methoxy-4-(3-methoxy-1-propenyl)-phenol (20), 3, 4, 5 trimethoxy-trans-cinnamic acid (21), p-methoxycinnamic acid (22), 4-acetoxy-3-methoxy-trans-cinnamic acid (23), and p-hydroxy-trans-cinnamic acid (24).
    CONCLUSIONS:
    Compounds 1, 14, 20-24 were isolated from the roots and rhizomes of N. incisum for the first time. Compounds 1 and 14 are sesquiterpenoid and coumarin, respectively, and 20-24 were phenylpropanoid compounds.
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