Dasycarpol
Dasycarpol(9beta-Hydroxyfraxinellone) shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM. Dasycarpol also shows moderate inhibitory activity on lung cancer cell line A549.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Molecules.2023, 28(9):3685.
Cell Chem Biol.2019, 26(1):27-34
Hortic Res.2023, 10(4):uhad039.
Plants (Basel).2021, 10(6):1192.
Enzyme Microb Technol.2022, 153:109941.
J Agric Food Chem.2024, 72(15):8784-8797.
Appl. Sci. 2021, 11(8),3437.
Sci Rep.2018, 8(1):12970
Antioxidants (Basel).2020, 9(6):544.
Korean Journal of Pharmacognosy2018, 49(1):76-83
Related and Featured Products
Bisacurone C
Catalog No: CFN89015
CAS No: 127214-86-2
Price: Inquiry(manager@chemfaces.com)
3-Hydroxybisabola-1,10-dien-9-one
Catalog No: CFN89024
CAS No: 129673-86-5
Price: Inquiry(manager@chemfaces.com)
3,4-Dihydroxybisabola-1,10-diene
Catalog No: CFN89025
CAS No: 129673-87-6
Price: Inquiry(manager@chemfaces.com)
1,4-Epidioxybisabola-2,10-dien-9-one
Catalog No: CFN89249
CAS No: 170380-69-5
Price: Inquiry(manager@chemfaces.com)
Bisabola-3,10-dien-2-one
Catalog No: CFN89224
CAS No: 61432-71-1
Price: Inquiry(manager@chemfaces.com)
1-Hydroxybisabola-2,10-dien-4-one
Catalog No: CFN96995
CAS No: 1213251-45-6
Price: Inquiry(manager@chemfaces.com)
4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one
Catalog No: CFN89244
CAS No: 170380-68-4
Price: Inquiry(manager@chemfaces.com)
9-Oxo-2,7-bisaboladien-15-oic acid
Catalog No: CFN97512
CAS No: 93888-59-6
Price: Inquiry(manager@chemfaces.com)
4-Hydroxy-1,10-secocadin-5-ene-1,10-dione
Catalog No: CFN96371
CAS No: 226904-40-1
Price: Inquiry(manager@chemfaces.com)
Bisabolangelone
Catalog No: CFN91876
CAS No: 30557-81-4
Price: $288/10mg
J Nat Prod. 2008 Feb;71(2):208-11.
Neuroprotective limonoids of root bark of Dictamnus dasycarpus.[Pubmed:
18198838]
METHODS AND RESULTS:
A methanolic extract of Dictamnus dasycarpus root bark afforded four new degraded limonoids, 9alpha-hydroxyfraxinellone-9- O-beta- d-glucoside ( 1), dictamnusine ( 2), dictamdiol A ( 3), and dictamdiol B ( 4), together with eight known compounds, dictamdiol ( 5), fraxinellone ( 6), fraxinellonone ( 7), 9beta-hydroxyfraxinellone (Dasycarpol,8), calodendrolide ( 9), obacunone ( 10), limonin ( 11), and rutaevin ( 12).
CONCLUSIONS:
Compounds, 2, 3, 6, 9, 10, and 11 showed significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM.
J Asian Nat Prod Res. 2005 Dec;7(6):843-5.
Microbial transformation of fraxinellone by Aspergillus niger.[Pubmed:
16308202 ]
METHODS AND RESULTS:
Microbial transformation of fraxinellone (1) by Aspergillus niger (AS 3.421) has been carried out. Two converted products, Dasycarpol (2) and a new compound fraxinigerllone (3) were obtained. Their structures have been identified on the basis of spectroscopic methods.
CONCLUSIONS:
Dasycarpol shows moderate inhibitory activity on lung cancer cell line A549.
