Dasycarpol
Dasycarpol(9beta-Hydroxyfraxinellone) shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM. Dasycarpol also shows moderate inhibitory activity on lung cancer cell line A549.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Korean Med Obes Res.2023, 23:10-7
J Chromatogr A.2017, 1518:46-58
Phytomedicine.2023, 120:155063.
J Nat Prod.2023, 86(2):264-275.
J Hematol Oncol.2018, 11(1):112
Molecules.2022, 27(22):7887.
Food Hydrocolloids2024, 156:110345
Toxins (Basel).2020, 12(4):210.
Metab Eng.2022, 75:143-152.
Integr Med Res.2017, 6(4):395-403
Related and Featured Products
J Nat Prod. 2008 Feb;71(2):208-11.
Neuroprotective limonoids of root bark of Dictamnus dasycarpus.[Pubmed:
18198838]
METHODS AND RESULTS:
A methanolic extract of Dictamnus dasycarpus root bark afforded four new degraded limonoids, 9alpha-hydroxyfraxinellone-9- O-beta- d-glucoside ( 1), dictamnusine ( 2), dictamdiol A ( 3), and dictamdiol B ( 4), together with eight known compounds, dictamdiol ( 5), fraxinellone ( 6), fraxinellonone ( 7), 9beta-hydroxyfraxinellone (Dasycarpol,8), calodendrolide ( 9), obacunone ( 10), limonin ( 11), and rutaevin ( 12).
CONCLUSIONS:
Compounds, 2, 3, 6, 9, 10, and 11 showed significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM.
J Asian Nat Prod Res. 2005 Dec;7(6):843-5.
Microbial transformation of fraxinellone by Aspergillus niger.[Pubmed:
16308202 ]
METHODS AND RESULTS:
Microbial transformation of fraxinellone (1) by Aspergillus niger (AS 3.421) has been carried out. Two converted products, Dasycarpol (2) and a new compound fraxinigerllone (3) were obtained. Their structures have been identified on the basis of spectroscopic methods.
CONCLUSIONS:
Dasycarpol shows moderate inhibitory activity on lung cancer cell line A549.
Hamaudol
Catalog No: CFN95115
CAS No: 735-46-6
Price: $268/10mg
Complanatoside C
Catalog No: CFN95144
CAS No: N/A
Price: $318/5mg
3,7,25-Trihydroxycucurbita-5,23-dien-19-al
Catalog No: CFN95150
CAS No: 85372-65-2
Price: $318/5mg
Momordicoside X
Catalog No: CFN95170
CAS No: 1333321-50-8
Price: $368/5mg
Astin B
Catalog No: CFN95188
CAS No: 151201-76-2
Price: $318/10mg
Tigloylgomisin O
Catalog No: CFN95237
CAS No: 130855-74-2
Price: $368/5mg
Saucerneol
Catalog No: CFN95267
CAS No: 88497-86-3
Price: $318/5mg
5,6,7,3',4'-Pentamethoxyflavanone
Catalog No: CFN95394
CAS No: 104193-93-3
Price: $318/5mg
3',4',5',5,7-Pentamethoxyflavanone
Catalog No: CFN95414
CAS No: 479672-30-5
Price: $218/20mg
Malabaricone A
Catalog No: CFN95477
CAS No: 63335-23-9
Price: $318/10mg
