Vibralactone D
Vibralactones D shows weak inhibitory activities against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD) with IC(50) values of 85.7 microM (human HSD1), 295.2 microM (mouse HSD1), and 87.1 microM (human HSD2).
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Korea Food Research Institute2024, 4798082
Int J Mol Sci.202, 25(17):9246.
Metabolites.2020, 11(1):E11.
J Pharm Biomed Anal.2019, 172:268-277
Int J Mol Sci.2021, 22(21):11836.
Sci Rep.2024, 14(1):26330.
National Academy Science Letters2023, s40009.
Evid Based Complement Alternat Med.2016, 2016:1739760
J Nat Prod.2015, 78(6):1339-4
J Ethnopharmacol.2024, 320:117426.
Related and Featured Products
Chem Pharm Bull (Tokyo). 2010 Jan;58(1):113-6.
Vibralactones D-F from cultures of the basidiomycete Boreostereum vibrans.[Pubmed:
20045978]
Three new metabolites, Vibralactone D, vibralactone E, vibralactone F (1-3) were isolated from cultures of the basidiomycete Boreostereum vibrans.
METHODS AND RESULTS:
The relative configuration of 1 was established on the basis of X-ray diffraction analysis, while the absolute configurations of 1-3 were assigned using a modified Mosher's method. Compound 1 showed weak inhibitory activities against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD) with IC(50) values of 85.7 microM (human HSD1), 295.2 microM (mouse HSD1), and 87.1 microM (human HSD2).
