Corchoionoside C

Corchoionoside C
Product Name Corchoionoside C
CAS No.: 185414-25-9
Catalog No.: CFN99859
Molecular Formula: C19H30O8
Molecular Weight: 386.4 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Targets: Histamine Receptor | Antifection
Source: The herbs of Polygonum hydropiper
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price:
Corchoionoside C has antioxidant activity, shows strong scavenging activities on DPPH radical, it also shows weak antifungal activity. Corchoionosides A, B, and C inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Study on the chemical constituents from Cibotium barometz and their scavenging activities for 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical.
    METHODS AND RESULTS:
    The chemical constituent from70% alcohol extract of C.barometz was isolated on chromatograph of silica gel and sephadex LH-20 and HPLC,their structure were elucidated on the basis of spectra data and the compounds were tested for their scavenging activities on DPPH radical.Ten compounds were purified and their structure were identified as 1-O-caffeyl-D-glucopyranose(1),6-O-caffeyl-D-glucopyranose(2),3-O-caffeyl-D-glucopyranose(3),3-hydroxymethyl-2(5H)-furanone(4),β-miroside(5),cibotiumbaroside A(6),protocatechuic acid(7),glucose(8),mannose(9),Corchoionoside C(10),kojic acid(11).Three isolated compounds showed strong scavenging activities on DPPH radical.
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    Compound 1-5 were isolated for the first time from C.barometz.among of them,compound 1,compound 3 and compound 6 showed significant antioxidant activity,and the scavenging activity of compound 1 was similar to that of Vit C.
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    METHODS AND RESULTS:
    Three new ionone glucosides named corchoionoside A, corchoionoside B, and Corchoionoside C were isolated from the leaves of Corchorus olitorius, commonly called "moroheiya" in Japanese, together with seven known compounds, an ionone glucoside (6S,9R)-roseoside, a monoterpene glucoside betulalbuside A, two flavonol glucosides astragalin and isoquercitrin, two coumarin glucosides scopolin and cichoriine, and chlorogenic acid. The absolute stereostructures of corchoionoside A, corchoionoside B, and Corchoionoside C were determined by chemical and physiochemical evidence, which included the result of application of a modified Mosher's method, the CD helicity rule, and chemical correlation with (6S,9R)-roseoside.
    CONCLUSIONS:
    Corchoionosides A and B and (6S,9R)-roseoside were found to inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
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