Corchoionoside C
Corchoionoside C has antioxidant activity, shows strong scavenging activities on DPPH radical, it also shows weak antifungal activity. Corchoionosides A, B, and C inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Front Pharmacol.2019, 10:1355
Phytomedicine.2020, 79, 153351
Toxicol In Vitro.2023, 86:105521.
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J Ethnopharmacol.2020, 254:112733.
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Chinese Journal of Experimental Traditional Medical Formulae, 2012, 18(24):162-6.
Chemical Constituents from Cibotium barometz and their Scavenging Activities for DPPH Radical.[Reference:
WebLink]
Study on the chemical constituents from Cibotium barometz and their scavenging activities for 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical.
METHODS AND RESULTS:
The chemical constituent from70% alcohol extract of C.barometz was isolated on chromatograph of silica gel and sephadex LH-20 and HPLC,their structure were elucidated on the basis of spectra data and the compounds were tested for their scavenging activities on DPPH radical.Ten compounds were purified and their structure were identified as 1-O-caffeyl-D-glucopyranose(1),6-O-caffeyl-D-glucopyranose(2),3-O-caffeyl-D-glucopyranose(3),3-hydroxymethyl-2(5H)-furanone(4),β-miroside(5),cibotiumbaroside A(6),protocatechuic acid(7),glucose(8),mannose(9),Corchoionoside C(10),kojic acid(11).Three isolated compounds showed strong scavenging activities on DPPH radical.
CONCLUSIONS:
Compound 1-5 were isolated for the first time from C.barometz.among of them,compound 1,compound 3 and compound 6 showed significant antioxidant activity,and the scavenging activity of compound 1 was similar to that of Vit C.
Nat Prod Res. 2011 Jan;25(1):1-7.
Isoswertisin flavones and other constituents from Peperomia obtusifolia.[Pubmed:
21240754 ]
METHODS AND RESULTS:
A phytochemical investigation of the leaves and stems of Peperomia obtusifolia (Piperaceae) yielded a new flavone C-diglycoside isoswertisin-4'-methyl-ether-2''α-L-rhamnoside (1), along with four known compounds: isoswertisin-2''α-L-rhamnoside (2), (+)-diayangambin (3), 2-episesalatin (4) and Corchoionoside C (5). The structures of the two flavone C-diglycosides (1, 2) were elucidated on the basis of 1D and 2D NMR spectroscopy and MS spectrometric data.
CONCLUSIONS:
These flavones were evaluated by bioautographic assay against Cladosporium cladosporioides and C. sphaerospermum and showed weak antifungal activity.
Molecules. 2010 Apr 12;15(4):2593-9.
A new sulfated alpha-ionone glycoside from Sonchus erzincanicus Matthews.[Pubmed:
20428066]
Sonchus erzincanicus (Asteraceae) is an endemic species in Turkey, where six Sonchus species grow.
METHODS AND RESULTS:
In this study, a phytochemical study was performed on the aerial parts of the plant. The study describes the isolation and structure elucidation of five flavonoids and two a-ionone glycosides from S. erzincanicus. The compounds were isolated using several and repeated chromatographic techniques from ethyl acetate and aqueous phases that were partitioned from a methanol extract obtained from the plant. 5,7,3',4'-Tetrahydroxy-3-methoxyflavone (1) and quercetin 3-O-beta-D-glucoside (2) were isolated from the ethyl acetate phase, while Corchoionoside C 6'-O-sulfate (3), Corchoionoside C (4), luteolin 7-O-glucuronide (5) and luteolin 7-O-beta-D-glucoside (6), apigenin 7-O-glucuronide (7) were isolated from the aqueous phase. Corchoionoside C 6'-O-sulfate (3), isolated for the first time from a natural source, was a new compound.
CONCLUSIONS:
The structures of the compounds were elucidated by means of 1H-NMR, 13C-NMR, 2D-NMR (COSY, HMQC, HMBC) and ESI-MS.
Chem Pharm Bull (Tokyo). 1997 Mar;45(3):464-9.
Medicinal foodstuffs. V. Moroheiya. (1): Absolute stereostructures of corchoionosides A, B, and C, histamine release inhibitors from the leaves of Vietnamese Corchorus olitorius L. (Tiliaceae).[Pubmed:
9085554]
METHODS AND RESULTS:
Three new ionone glucosides named corchoionoside A, corchoionoside B, and Corchoionoside C were isolated from the leaves of Corchorus olitorius, commonly called "moroheiya" in Japanese, together with seven known compounds, an ionone glucoside (6S,9R)-roseoside, a monoterpene glucoside betulalbuside A, two flavonol glucosides astragalin and isoquercitrin, two coumarin glucosides scopolin and cichoriine, and chlorogenic acid. The absolute stereostructures of corchoionoside A, corchoionoside B, and Corchoionoside C were determined by chemical and physiochemical evidence, which included the result of application of a modified Mosher's method, the CD helicity rule, and chemical correlation with (6S,9R)-roseoside.
CONCLUSIONS:
Corchoionosides A and B and (6S,9R)-roseoside were found to inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
