Boscialin
Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Materials Today Communications2023, 37:107216
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Molecules.2022, 27(5):1675
BMC Complement Altern Med.2014, 14:242
Cell Rep.2020, 32(11):108158.
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J Asian Nat Prod Res. 2015;17(6):615-24.
Wilfordonols A-D: four new norsesquiterpenes from the leaves of Tripterygium wilfordii.[Pubmed:
26096035 ]
METHODS AND RESULTS:
Four new norsesquiterpenes wilfordonols A-D (1-4), along with three known compounds, sarmentol B (5), Boscialin (6), and (+)-loliolide (7), were isolated from the leaves of Tripterygium wilfordii Hook.f.. The structures of the new compounds were elucidated on the basis of their spectroscopic analysis, and the absolute configuration of the compounds was confirmed by CD and modified Mosher's method.
CONCLUSIONS:
At a concentration of 10 μM, compounds 4, 6, and 7 inhibited signal transducer and activator of transcription 1 translocation by 34.27 ± 1.02%, 48.93 ± 1.76%, and 70.31 ± 2.20%, respectively.
