Anthriscusin
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Chem Pharm Bull (Tokyo). 1998 May;46(5):871-4.
Antiproliferative constituents in umbelliferae plants. III. Constituents in the root and the ground part of Anthriscus sylvestris Hoffm.[Pubmed:
9621422]
METHODS AND RESULTS:
The MeOH extract of the root and the ground part of Anthriscus sylvestris Hoffm. showed a high inhibitory activity against MK-1, HeLa, and B16F10 cell growth in vitro. The activity was found only in the CHCI3-soluble fractions. From the CHCI3-soluble fraction of the root, falcarindiol, 1-(3'-methoxy-4',5'-methylenedioxyphenyl)-1 xi-methoxy-2-propene, elemicin, and nemerosin were newly isolated in addition to deoxypodophyllotoxin (anthricin), Anthriscusin, (-)-deoxypodorhizone, and anthriscinol methyl ether which were reported earlier as constituents of the root of this plant.
CONCLUSIONS:
From the CHCI3-soluble fraction of the ground part, deoxypodophyllotoxin, (-)-deoxypodorhizone, nemerosin, and falcarindiol were isolated. In vitro antiproliferative activities of the isolates against MK-1, HeLa, and B16F10 cells are reported.
Chemical & Pharmaceutical Bulletin, 2008 , 26 (4) :1337-1338.
Structure of Anthriscusin, a New Phenylpropanoid Ester from the Roots of Anthriscus sylvestris HOFFM.[Reference:
WebLink]
METHODS AND RESULTS:
A new phenylpropanoid ester, Anthriscusin was isolated from the roots of Anthriscus sylvestris HOFFM. (Umbelliferae), and was elucidated as O-[(Z)-2-angeloyloxymethyl-2-butenoyl]-3-methoxy-4,5-methylenedioxycinnamyl alcohol on the basis of the spectral data and the chemical evidence.