Angeloylgomisin O

Angeloylgomisin O
Product Name Angeloylgomisin O
CAS No.: 83864-69-1
Catalog No.: CFN89067
Molecular Formula: C28H34O8
Molecular Weight: 498.57 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The fruits of Schizandra chinensis BAILL.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $288/10mg
Angeloylgomisin O is a nartural product from Schisandra chinensis.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Antioxidants (Basel).2022, 11(12):2327.
  • Prev Nutr Food Sci.2024, 29(4):563-571.
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • Sci Rep.2018, 8(1)
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • Bioorg Chem.2024, 152:107720.
  • Front Plant Sci.2021, 12: 648426.
  • Front Immunol.2020, 11:598556.
  • Universite de Bordeaux2017, 2017BORD0867
  • Nutrients2020, 12(3):811.
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    The Antiproliferative Effects of Compounds Isolated from Schisandra chinensis.[Reference: WebLink]
    We isolated twelve lignans and three terpenoids were isolated from the n-hexane fraction of Schisandra chinensis extract.
    METHODS AND RESULTS:
    Using spectroscopic data and comparison with available literature, the following compounds were identified: (1) wuweizisu C, (2) gomisin N, (3) deoxyschisandrin, (4) gomisin A, (5) schisandrin, (6) chamigrenal, (7) schisanlactone D, (8) methylgomisin O, (9) Angeloylgomisin O, (10) (-)-gomisin L2, (11) schisandronic acid, (12) (-)-gomisin L1, (13) (+)-gomisin K3, (14) gomisin J, and (15) tigloylgomisin H. Notably, this was the first finding that compound (8) was isolated from this plant. Each compound was evaluated for its in vitro cytotoxic activities toward HL-60 (human leukemia), HeLa (human cervical carcinoma), and MCF-7 (breast cancer) cell lines. Compounds (7), (8), and (9) exhibited strong cytotoxic effects on HL-60 (IC50 7.37, 6.60, and 8.00 μM, respectively), whereas compound (6) exhibited weak cytotoxicity towards MCF-7 (IC50 30.50 μM). In addition, compound (8) showed the strongest activity towards HeLa cells (IC50 1.46 μM).
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    Three new dibenzocyclooctadiene lignans, Angeloylgomisin O (1), and angeloyl-(2) and benzoylisogomisin O (3) were isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae). Their absolute structures were elucidated by means of chemical and spectral studies.
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