Angelic acid
Angelic acid is a monocarboxylic unsaturated organic acid, which is useful as perfume materials.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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AMB Express2020. 10(1):126.
J Ethnopharmacol.2024, 318(Pt B):116961.
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Toxicol In Vitro.2023, 93:105667.
Tropical J. of Pha. Research2017, 16(3):543-552
Int J Mol Sci.2023, 24(8):7300.
J.Pharm. & Biome. Anal.2023, 2: 100018.
Applied Biological Chemistry2021, 64(4)
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Volume 18, Issue 10, 17 September 1979, Pages 1647-1649
The biosynthesis of angelic acid in Cynoglossum officinale[Reference:
WebLink]
METHODS AND RESULTS:
Six-month-old Cynoglossum officinale plants were fed via the roots with tiglic acid-[1-14C]. After a week the plants were harvested, the alkaloid heliosupine was isolated and hydrolysed to heliotridine and Angelic acid. <
CONCLUSIONS:
The latter contained all the radioactivity of the original heliosupine showing that Angelic acid may be formed from tiglic acid by a cis-trans isomerization.
US 4613680 A[P]. 1986.
PROCESS FOR PREPARING ANGELIC ACID OR ITS ESTER[Reference:
WebLink]
Angelic acid or esters thereof which are useful as perfume materials are prepared by isomerizing tiglic acid or an ester thereof with an organic sulfinic acid as the catalyst, and novel esters of Angelic acid represented by the formula wherein R represents 3-hexenyl, 3-methyl-2-butenyl, 3-methyl-3-butenyl, 3-methyl-2-pentenyl, 3-methyl-4-pentenyl, CH3(CH2)l- (in which l is an integer from 5 to 9), cyclopentyl, cyclohexyl, 2-methylpentyl, alpha -methylbenzyl, neryl or furfuryl are provided as part of said esters of Angelic acid.
