Aburatubolactam A

Aburatubolactam A
Product Name Aburatubolactam A
CAS No.: 170894-24-3
Catalog No.: CFN00101
Molecular Formula: C30H40N2O5
Molecular Weight: 508.66 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Oil
Targets: Immunology & Inflammation related
Source: From Streptomyces sp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Aburatubolactam A is an inhibitor of superoxide anion generation. It has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Aburatubolactam A is a tetramic acid macrolactam isolated by Uemura and coworkers in 1996 from the cultured broth of a sp., SCRC-A20, taken from the surface of a mollusk collected on the seashore near Aburatubo, Kanagawa Prefecture, Japan.
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    Aburatubolactam A has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC= 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils. Enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging. Unfortunately, inadequate quantities of material were isolated to allow broader testing.
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