Discodermide
Discodermide has antifungal and cytotoxic activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Med Chem.2023, 66(6):4106-4130.
Kangwon National University2022, 37(1):29-37
Journal of Molecular Liquids2022, 364:120062.
Front Pharmacol.2017, 8:205
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Food Structure2023, 36:100324.
Front Cell Dev Biol.2020, 8:32.
Metabolites.2019, 9(11):E271
Sci Rep.2023, 13(1):13610.
Trop J Nat Prod Res, February2023, 7(2):2371-2381
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J. Org. Chem., 1991, 56(16):4833-40
Discodermide: A new bioactive macrocyclic lactam from the marine sponge Discodermia dissoluta[Reference:
WebLink]
METHODS AND RESULTS:
A new macrocyclic lactam, Discodermide (1), was isolated from a Caribbean marine sponge, Discodermia dissoluta. Its structure was elucidated through a combination of spectroscopic techniques, in particular NMR spectroscopy.
CONCLUSIONS:
The carbon skeleton displayed by Discodermide is new; Discodermide is antifungal and cytotoxic.
