8'-Oxo-6-hydroxydihydrophaseic acid
8'-Oxo-6-hydroxydihydrophaseic acid is a natural product from Illicium dunnianum.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Asian Nat Prod Res. 2012;14(10):940-9.
Sesquiterpenes and neolignans from the roots of Illicium dunnianum.[Pubmed:
23046465 ]
METHODS AND RESULTS:
Two new sesquiterpenes, dunnianoside I (1) and 8'-Oxo-6-hydroxydihydrophaseic acid methyl ester (2), a new glycoside, dunnianoside J (3), two new neolignans, dunnianeolignans A-B (4, 5), together with 10 known compounds (6-15), were isolated from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-ESI-MS, and chemical methods.
CONCLUSIONS:
Compounds 7, 8, and 13-15 exhibited potent antioxidant activities against Fe2⁺-cystine-induced rat liver microsomal lipid peroxidation, with IC₅₀ values ranging from 4.2 ± 0.4 to 38.4 ± 2.6 μM.
