Dihydrophaseic acid

Dihydrophaseic acid
Product Name Dihydrophaseic acid
CAS No.: 41756-77-8
Catalog No.: CFN98657
Molecular Formula: C15H22O5
Molecular Weight: 282.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Echinocystis macrocarpa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Dihydrophaseic acid 3’-O-b-D-glucopyranoside (D3G) can increase the proliferation and differentiation of osteoblast cells and enhance bone formation, suggests that D3G may be a good candidate for the treatment of osteoporosis.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Metabolites.2019, 9(11):E271
  • Journal of Functional Foods2019, 52:430-441
  • Front Pharmacol.2018, 9:756
  • Chem Biol Interact.2016, 258:59-68
  • Appl. Sci.2023, 13(17):9984.
  • Int J Mol Sci.2017, 18(12)
  • Molecules.2023, 28(4):1526.
  • J Mol Recognit.2020, 33(2):e2819
  • Molecules.2019, 24(24):E4536
  • J. of Med. Plant Research.2013, 90-151
  • Abscisic acid

    Catalog No: CFN90051
    CAS No: 21293-29-8
    Price: $40/20mg
    8'-O-(3-hydroxy-3-methylglutaryl)-8'-hydroxyabscisic acid

    Catalog No: CFN95308
    CAS No: 69790-31-4
    Price: $318/5mg
    Breyniaionoside A

    Catalog No: CFN96810
    CAS No: 823182-23-6
    Price: Inquiry(manager@chemfaces.com)
    Cucumegastigmane I

    Catalog No: CFN97498
    CAS No: 929881-46-9
    Price: $318/5
    Apocynol A

    Catalog No: CFN97750
    CAS No: 358721-33-2
    Price: Inquiry(manager@chemfaces.com)
    Megastigm-7-ene-3,5,6,9-tetraol

    Catalog No: CFN98335
    CAS No: 680617-50-9
    Price: Inquiry(manager@chemfaces.com)
    7-Megastigmene-3,5,6,9-tetraol

    Catalog No: CFN98334
    CAS No: 276870-26-9
    Price: Inquiry(manager@chemfaces.com)
    Euscaphin B

    Catalog No: CFN97536
    CAS No: 956869-95-7
    Price: Inquiry(manager@chemfaces.com)
    Megastigm-7-ene-3,4,6,9-tetrol

    Catalog No: CFN96244
    CAS No: 180164-14-1
    Price: Inquiry(manager@chemfaces.com)
    cis-3,4-Dihydroxy-beta-ionone

    Catalog No: CFN96404
    CAS No: 875666-39-0
    Price: Inquiry(manager@chemfaces.com)
    Osteoporosis and Sarcopenia 2015,1(2):137-8.
    Antiosteoporotic Activity of Dihydrophaseic Acid 3′-O-b-D-Glucopyranoside Derivatives from Lycii Radicis Cortex.[Reference: WebLink]
    Our previous study demonstrated that ethanol extract of Lycii Radicis Cortex (LRC) prevented the ovariectomized-induced bone mineral density loss in mice via promoting the differentiation of osteoblast linage cells. A single compound, D3G, was isolated from the LRC extract as a candidate component enhancing bone formation. The aim of this study was to investigate the antiosteoporotic effects of Dihydrophaseic acid 3ʹ-O-b-D-glucopyranoside (D3G).
    METHODS AND RESULTS:
    The highest alkaline phosphatase activity was observed with 5 μg/ml of D3G in both cell lines: C3H10T1/2 and MC3T3-E1. The D3G treatment for 21 days increased the mineralized nodule formation in the MC3T3-E1 cell line. The expression of osteoblastic markers, Alpl, Runx2, and Bglap, was significantly increased in the D3G-treated cells compared to the non-treated control cells. The D3G treatment did not influence osteoclast differentiation in primary-cultured monocytes of mouse bone marrow. In coculture of monocytes and MC3T3-E1 cells, however, D3G induced both osteoblast and osteoclast differentiation.
    CONCLUSIONS:
    This study demonstrated that D3G increased the proliferation and differentiation of osteoblast cells and enhanced bone formation. These results suggest that D3G may be a good candidate for the treatment of osteoporosis
    Plant Physiol. 1981 Jul;68(1):93-5.
    Identification of a dihydrophaseic Acid aldopyranoside from soybean tissue.[Pubmed: 16661896 ]

    METHODS AND RESULTS:
    A previously unidentified abscisic acid metabolite has been isolated and characterized. (+/-)-[2-(14)C]Abscisic acid was incubated in intact soybean leaves and pods; the radiolabeled metabolite was purified by high performance liquid chromatography with on-line scintillation spectrometry detection. Gas chromatography-mass spectrometry was used to obtain spectra of the acetylated and methyl esterified derivatives.
    CONCLUSIONS:
    The data were consistent with a proposed Dihydrophaseic acid-aldopyranoside identity. Conjugation through the 4'-hydroxyl of Dihydrophaseic acid is suggested.
    Isocarlinoside

    Catalog No: CFN95092
    CAS No: 83151-90-0
    Price: $318/5mg
    Oleuroside

    Catalog No: CFN95099
    CAS No: 116383-31-4
    Price: $288/20mg
    Pueroside B

    Catalog No: CFN95141
    CAS No: 100692-54-4
    Price: $288/10mg
    3-Hydroxy-4',5-dimethoxystilbene

    Catalog No: CFN95199
    CAS No: 58436-29-6
    Price: $318/10mg
    Stevioside D

    Catalog No: CFN95230
    CAS No: 1310055-59-4
    Price: $463/5mg
    Planispine A

    Catalog No: CFN95348
    CAS No: 1202761-42-9
    Price: $318/10mg
    Fragransin B1

    Catalog No: CFN95443
    CAS No: 112516-03-7
    Price: $318/5mg
    Cagayanin

    Catalog No: CFN95480
    CAS No: 99096-51-2
    Price: $318/20mg
    Ganolucidic acid B

    Catalog No: CFN95513
    CAS No: 98683-75-1
    Price: $413/5mg
    Methyl ganoderate A

    Catalog No: CFN95550
    CAS No: 105742-78-7
    Price: $413/5mg