5-Heptadecylresorcinol
5-Heptadecylresorcinol has strong inhibitory property against the growth of PC3 cells.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Food Chemistry.2012 130(1):156-64.
Wheat bran lipophilic compounds with in vitro anticancer effects.[Reference:
WebLink]
Wheat bran has been widely recognised as a cancer preventive agent, although the mechanism of the protection is not yet fully understood. Some reports suggested that, for the protection, lipophilic phytochemicals from the bran were more important than the physiological function of bran fibre.
METHODS AND RESULTS:
Wheat bran lipophilic extracts were scrutinised using bioactivity-guided fractionation (HPLC) against the growth of human prostate adenocarcinoma (PC3) cells. The fractions containing unsaturated free fatty acid, phytosteroids and alkylresorcinols exerted high cytotoxic activity. Detailed research of the alkylresorcinol fraction isolated seven pure compounds, four of them with strong inhibitory properties against the growth of PC3 cells, including 5-Heptadecylresorcinol.
