5,7,4'-Trimethoxyafzelechin | CAS:918428-88-3

Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

European Journal of Integrative Medicine2018, 20:165-172

Korean J of Medicinal Crop Science2018, 220-226

Korean Journal of Plant Resources2021, 34(1):52-58.

Mol Plant Pathol.2022, 10.1111:mpp.13280.

Int J Mol Sci.2023, 24(7):6360.

EXCLI J.2023, 22:482-498.

Oncotarget.2016, 8(51):88386-88400

Cell Rep.2022, 39(1):110643.

Phytomedicine.2021, 2(82):153452

Rec. Nat. Prod.2024, 18:4,405-418.

J Oleo Sci. 2008;57(8):431-5.

Alpha-glucosidase inhibitor from Bergenia ligulata.[Pubmed: 18622126]

Inhibitory compound of alpha-glucosidase activity, (+)-afzelechin (1), was isolated from rhizomes of Bergenia ligulata.
METHODS AND RESULTS:
The structure was identified by IR, EI-MS, (1)H and (13)C NMR spectroscopy. The ID(50) (50% inhibition dose) value of compound 1 was 0.13 mM. To investigate the structure-activity relationship, (+)-afzelechin tetraacetate (2), (+)-5,7,4'-Trimethoxyafzelechin (3), (+)-tetramethoxyafzelechin (4), and (+)-3-acetyl-5,7,4'-Trimethoxyafzelechin (5) as the derivatives of compound 1 were evaluated as well.

Product Name	5,7,4'-Trimethoxyafzelechin
CAS No.:	918428-88-3
Catalog No.:	CFN92954
Molecular Formula:	C₁₈H₂₀O₅
Molecular Weight:	316.35 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Celastrus orbiculatus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: