Catechin 3-rhamnoside | CAS:103630-03-1

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Three - (-) Catechin-O-Rhamnosides from the Eastern Nigeria Mistletoe with Potent Immunostimulatory and Antioxidant Activities[Reference: WebLink]

In an attempt to provide further convincing evidence for the variously reported immunomodulatory potentials of mistletoes, bioassay-guided fractionation of the eastern Nigeria mistletoe afforded three compounds: - (-) catechin- 7-O-rhamnoside (1), - (-) catechin-3-O- rhamnoside (Catechin 3-rhamnoside,2) and a 4′-methoxy-7-O-rhamnoside (3).
METHODS AND RESULTS:
Their effects on C57BL6 mice splenocytes proliferation and expression of CD69 molecule were determined using flow cytometry techniques and compared to Lipopolysaccharide (LPS; 10 μg/ml) and Concanavalin A (ConA; 2 μg/ml) as standards. The antioxidant study was by the DPPH model with ascorbic acid as standard. The compounds (1-3) at 100 μg/ml showed statistically significant (p<0.05) stimulatory activity with values of 91.49 Â± 0.22%, 95.17 Â± 0.01% and 94.23 Â± 0.07% respectively compared to 2.65 Â± 0.33% for the unstimulated control. However, the CD69 expression assay showed only moderate stimulation. Their measured antioxidant potentials (effective concentration; EC50) were high (≤ 55.42 Â± 0.99 mg/ml) when compared to ascorbic acid (17.6 Â± 1.78 mg/ml). Characterization of the compounds was achieved by chromatographic and spectroscopic methods.

Product Name	Catechin 3-rhamnoside
CAS No.:	103630-03-1
Catalog No.:	CFN99052
Molecular Formula:	C₂₁H₂₄O₁₀
Molecular Weight:	436.4 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The stems of Erythroxylum novogranatense
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
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