4'-O-Methylbroussochalcone B

4'-O-Methylbroussochalcone B
Product Name 4'-O-Methylbroussochalcone B
CAS No.: 20784-60-5
Catalog No.: CFN98046
Molecular Formula: C21H22O4
Molecular Weight: 338.4 g/mol
Purity: >=98%
Type of Compound: Chalcones
Physical Desc.: Yellow powder
Source: The seeds of Psoralea corylifolia Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $198/20mg
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Journal of Chromatography A2020, 460942
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Appl. Sci.2020, 10,1304
  • Cell Chem Biol.2019, 26(1):27-34
  • J Sep Sci.2018, 41(11):2488-2497
  • Eur J Pharm Sci.2016, 94:33-45
  • Chem Pharm Bull (Tokyo).2019, 67(11):1242-1247
  • Inflammation.2015, 38(4):1502-16
  • Phytochemistry.2017, 141:162-170
  • ACS Nano.2018, 12(4):3385-3396
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