4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan | CAS:1206464-65-4

4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan shows cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15).

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Cytotoxic lignans from Viburnum foetidum.[Pubmed: 23881703 ]

METHODS AND RESULTS:
Two new lignans, 3,4,4'-trihydroxy-3',9-dimethoxy-9,9'-epoxylignan (1), 3,4'-dihydroxy-3',4, 9-trimethoxy-9,9'-epoxylignan (2), together with one known compound, 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan (3), were isolated from the 95 % EtOH extract of Viburnum foetidum. The structures of the two new compounds were elucidated on the basis of 1D, 2D-NMR, and mass spectral analysis.
CONCLUSIONS:
All the lignans were in vitro evaluated for their cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15).

Product Name	4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan
CAS No.:	1206464-65-4
Catalog No.:	CFN96711
Molecular Formula:	C₂₁H₂₆O₆
Molecular Weight:	374.43 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The herbs of Viburnum foetidum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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