3'-Methylflavokawin | CAS:1044743-35-2

Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Res Rep Urol.2022, 14:313-326.

J Ethnopharmacol.2024, 324:117775.

Turk J Med Sci.2023 53: 1312-1320.

Int J Mol Sci.2018, 19(9):E2601

Biochem Biophys Res Commun.2020, 522(4):1052-1058

Chem Biodivers.2023, 20(10):e202300741.

J Integr Plant Biol.2023, 13564.

Processes2021, 9(1), 153;

Sci Rep.2023, 13(1):13072.

J Agric Food Chem.2020, 68(51):15164-15175

J Nat Prod. 2008 Jul;71(7):1237-41.

Synthesis, cytotoxicity, and antioxidative activity of minor prenylated chalcones from Humulus lupulus.[Pubmed: 18611049]

METHODS AND RESULTS:
The minor hop ( Humulus lupulus) chalcones 3'-geranylchalconaringenin (3), 5'-prenylxanthohumol (4), flavokawin (5), xanthohumol H (8), xanthohumol C (9), and 1'',2''-dihydroxanthohumol C (10) were synthesized. The non-natural chalcones 3'-geranyl-6'-O-methylchalconaringenin (2), 3'-Methylflavokawin (6), and 2'-O-methyl-3'-prenylchalconaringenin (7) were also synthesized. Cytotoxicity was investigated in HeLa cells, and these compounds all had IC 50 values comparable to xanthohumol (8.2-19.2 microM).
CONCLUSIONS:
The ORAC-fluorescein assay revealed potent antioxidative activity for 7 and 8 with 5.2 and 4.8 Trolox equivalents, respectively.

Product Name	3'-Methylflavokawin
CAS No.:	1044743-35-2
Catalog No.:	CFN96084
Molecular Formula:	C₁₈H₁₈O₅
Molecular Weight:	314.3 g/mol
Purity:	>=98%
Type of Compound:	Chalcones
Physical Desc.:	Yellow powder
Source:	The herbs of Humulus lupulus
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: