3-Epidehydrotumulosic acid

3-Epidehydrotumulosic acid
Product Name 3-Epidehydrotumulosic acid
CAS No.: 167775-54-4
Catalog No.: CFN92743
Molecular Formula: C31H48O4
Molecular Weight: 484.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Wolfiporia cocos (Schw.) Ryv.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $368/5mg
3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Int J Biol Macromol. 2018 Feb 12.
  • Evid Based Complement Alternat Med. 2017:6360836.
  • Tea Res. Ins. Of ChinaJuly 13, 2017;
  • PhytomedicineFeb. 11. 2016
  • Biofactors.2017 Oct 24.
  • Molecules.2013 Jun 24;18(7):7376-88.
  • Neuropharmacology.2018 Mar 15;
  • Evid Based Complement Alternat Med. 2017:1583185
  • Food Science and Bio.31 October 2016
  • BMC Complement Altern Med.2014 Jul 14;14:242.
  • Eburicoic acid

    Catalog No: CFN90414
    CAS No: 560-66-7
    Price: Inquiry(manager@chemfaces.com)
    Pachymic acid

    Catalog No: CFN99590
    CAS No: 29070-92-6
    Price: $268/20mg
    Dehydroeburicoic acid

    Catalog No: CFN92740
    CAS No: 6879-05-6
    Price: $416/10mg
    Dehydrotumulosic acid

    Catalog No: CFN92837
    CAS No: 6754-16-1
    Price: $338/5mg
    Dehydropachymic acid

    Catalog No: CFN92742
    CAS No: 77012-31-8
    Price: $338/10 mg
    3-Epidehydrotumulosic acid

    Catalog No: CFN92743
    CAS No: 167775-54-4
    Price: $368/5mg
    3-Epidehydropachymic acid

    Catalog No: CFN92738
    CAS No: 168293-15-0
    Price: $338/5mg
    Peroxydehydrotumulosic acid

    Catalog No: CFN92836
    CAS No: 943225-53-4
    Price: Inquiry(manager@chemfaces.com)
    Polyporenic acid C

    Catalog No: CFN92739
    CAS No: 465-18-9
    Price: $338/5mg
    16-O-Acetylpolyporenic acid C

    Catalog No: CFN96159
    CAS No: 2535-06-0
    Price: Inquiry(manager@chemfaces.com)
    J Nat Prod. 2002 Apr;65(4):462-5.
    Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.[Pubmed: 11975480]
    The structures of two novel 3,4-seco-lanostane-type triterpenes isolated from the sclerotium of Poria cocos were established to be 16alpha-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1; poricoic acid G) and 16alpha-hydroxy-3,4-seco-24-methyllanosta-4(28),8,24(24(1))-triene-3,21-dioic acid (2; poricoic acid H) on the basis of spectroscopic methods.
    METHODS AND RESULTS:
    These two, and eight other known compounds isolated from the sclerotium, poricoic acid B (3), poricoic acid A (4), tumulosic acid (5), dehydrotumulosic acid (6), 3-Epidehydrotumulosic acid (7), polyporenic acid C (8), 25-hydroxy-3-Epidehydrotumulosic acid (9), and dehydroabietic acid methyl ester (10), showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Evaluation of the cytotoxicity of compounds 1 and 4 against human cancer cell lines revealed that 1 was significantly cytotoxic to leukemia HL-60 cells [GI(50) (concentration that yields 50% growth) value 39.3 nM], although it showed only moderate cytotoxicity to the other cells. Compound 4 exhibited moderate cytotoxicity to all of the cancer cell lines tested.
    Phytother Res. 2003 Feb;17(2):160-2.
    Inhibitory effects of triterpenes isolated from Hoelen on free radical-induced lysis of red blood cells.[Pubmed: 12601680]
    Hoelen, sclederma of Poria cocos Wolf, has long been used as a sedative and diuretic in traditional medicine. Formerly, we demonstrated that Hoelen in vitro protects red blood cells from AAPH-induced hemolysis.
    METHODS AND RESULTS:
    In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-Epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-o-acetyl-16 alpha -hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.
    Afzelin

    Catalog No: CFN98757
    CAS No: 482-39-3
    Price: $288/20mg
    Conduritol A

    Catalog No: CFN98868
    CAS No: 526-87-4
    Price: $258/10mg
    Vicenin -2

    Catalog No: CFN92031
    CAS No: 23666-13-9
    Price: $198/10mg
    Ginsenoside F4

    Catalog No: CFN90757
    CAS No: 181225-33-2
    Price: $318/10mg
    Bruceine E

    Catalog No: CFN89340
    CAS No: 21586-90-3
    Price: $318/5mg
    Epimagnolin A

    Catalog No: CFN90949
    CAS No: 41689-51-4
    Price: $268/10mg
    Angelol A

    Catalog No: CFN90999
    CAS No: 19625-17-3
    Price: $198/10mg
    2''-O-Galloylquercitrin

    Catalog No: CFN95041
    CAS No: 80229-08-9
    Price: $418/5mg
    2''-O-acetylsaikosaponin A

    Catalog No: CFN95085
    CAS No: 102934-42-9
    Price: $318/5mg
    6''-O-Acetylsaikosaponin D

    Catalog No: CFN95090
    CAS No: 64340-45-0
    Price: $288/5mg