2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one

2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one
Product Name 2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one
CAS No.: 1809980-25-3
Catalog No.: CFN95197
Molecular Formula: C18H24O5
Molecular Weight: 320.4 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Curcuma phaeocaulis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/10mg
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Chinese Journal of Medicinal Chemistry, 2015.
    Isolation and identification of terpenoids from Myrrh.[Reference: WebLink]

    METHODS AND RESULTS:
    The chemical constituents from the CHCl3 extract of Commiphora opobalsamum were isolated and purified by various kind of column chromatography on silica gel,Sephadex LH-20 and ODS,and their structures were elucidated by the physico-chemical characters and the spectroscopic analysis. Twelve compounds were obtained and identified as proximadiol( 1),orientalol E( 2),alismol( 3),guaianediol( 4),( 1( 10) E,2R*,4R*,5S*)-2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one( 5),( 1( 10) E,2R*,4R*)-2- methoxy-8,12-epoxygermacra-1( 10),7,11-trien-6-one( 6),myrrhone( 7),dihydropyrocurzerenone( 8),cycloartane-1α,2α,3β,25-tetrol( 9),cycloartan-24-ene-1α,2α,3β-triol( 10),cycloartan-24-ene-1α,3β-diol( 11),and 29-norlanost-8,24-dien-1α,2α,3β-triol( 12),respectively. Compounds 1- 3 were isolated from Commiphora for the first time. All the isolated compounds were evaluated for their cytotoxicity against the PC-3hunman prostate tumor cell line.
    CONCLUSIONS:
    Only compounds 10 and 12 exhibited weak cytoxicity with IC50 values of37. 4 μmol·L~(-1),26. 2 μmol·L~(-1),respectively.
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