1(10)-Aristolen-2-one
1(10)-Aristolen-2-one has antifungal activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Journal of Multidisciplinary Engineering Science and Technology (JMEST), 2016, 3(7):5331-5.
Antifungal Activity of the Essential Oil of Elionurus Muticus (Spreng) Kunth from Zimbabwe against Candida albicans, C. krusei and Cryptococcus neoformans[Reference:
WebLink]
METHODS AND RESULTS:
Cultivated Elionurus muticus (Spreng.) Kunth (Gramineae) plant parts were steam distilled for essential oil and evaluated in-vitro for antifungal activity against Candida albicans, C. krusei and Cryptococcus neoformans using agar broth dilution and disc diffusion methods and the activity compared with commercial citral and Cymbopogon citratus DC (Stapf) (lemongrass) oils by measuring the growth inhibition diameter. E. muticus oils showed fungicidal activity with MIC and MFC values between 0.5-10μg/mL. E. muticus whole plant oil showed greater antifungal activity against C. albicans than citral and lemongrass oils. E. muticus whole plant essential oil contains citral and ∆ 1(10)-Aristolen-2-one as major components, both are known antifungal compounds.
CONCLUSIONS:
Their unique presence in one plant extract could have significant impact in treating mycotic diseases and other opportunistic infections and for use in clinical aromatherapy and in complementary and alternative medicines.
Analytical Chemistry Letters, 2012, 2(3):177-181.
Constituents of the Root Essential Oil of Cultivated Elionurus muticus (Spreng.) Kurth from Zimbabwe.[Reference:
WebLink]
METHODS AND RESULTS:
The roots of cultivated Elionurus muticus (Spreng.) Kurth (Gramineae) from Zimbabwe were hydrodistilled and analyzed by GC, GC-MS, 1H-NMR, and 13C-NMR.
CONCLUSIONS:
Forty four components were identified and the major component was an oxygenated sesquiterpene 1(10)-Aristolen-2-one (72.1 %).
