Hot Products

Sanggenone D
Catalog No: CFN99704

Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 cells at > 10 uM; inhibition of nitric oxide production was mediated by suppression of iNOS enzyme induction but not by direct inhibition of iNOS enzyme activity.

Sanggenone H
Catalog No: CFN90836

Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α and IL-1β and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.

Sanggenone K
Catalog No: CFN92416

Reference standards.

Sanguinarine
Catalog No: CFN98259

Sanguinarine possesses anticancer, antimicrobial, anti-inflammatory, and antioxidant properties, it has therapeutic potential in preventing the neurodegenerative diseases, it may be used to develop a potential therapeutic drug for treating cardiac remodeling and heart failure and shows protective effects on teeth and alveolar bone health. Sanguinarine can inhibit osteoclast formation and bone resorption via suppressing RANKL-induced activation of NF-κB and ERK signaling pathways, and can protect against cardiac hypertrophy and fibrosis via inhibiting NF-κB activation.

Sanguinarine chloride
Catalog No: CFN80234

Sanguinarine chloride is a novel class of anti-Salmonella compounds, it could decrease the production of the SPI-1 type III secretion system main virulence proteins SipA and SipB and prevent the invasion of HeLa cells by Salmonella enterica serovar Typhimurium without affecting the growth of Salmonella. Sanguinarine chloride also shows cytotoxicity to cultured human cells from oral tissue.

Sanguisorbigenin
Catalog No: CFN91139

Reference standards.

Santalol
Catalog No: CFN93131

α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly, it shows a significant antifungal effect against a dermatophytic fungus, Trichophyton rubrum. Santalol has good antibacterial, anti-oxidation and anti-tumor activities.

Santamarine
Catalog No: CFN98667

Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity against clinical strains of Mycobacterium tuberculosis.

Saponarin
Catalog No: CFN90134

Saponarin shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver damage. Saponarin exerts anti-inflammatory effects in LPS-induced RAW 264.7 macrophages via inhibition of NF-κB, ERK and p38 signaling.Saponarin is characterized as α-glucosidase inhibitor present in Tinospora cordifolia, it also has hypoglycemic activity in the range of 20-80 mg/kg compared to 100-200 mg/kg for acarbose as reported.Saponarin also exerts slight antihypertensive activity in non-diabetic spontaneously hypertensive rats (SHR).

Saponin
Catalog No: CFN70204

Tea saponins could modify the rumen fermentation and inhibit the release of methane and ammonia, which may be beneficial for improving nutrient utilization and animal growth.