Puerol B

Puerol B
Product Name Puerol B
CAS No.: 112343-17-6
Catalog No.: CFN95155
Molecular Formula: C18H16O5
Molecular Weight: 312.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The stem barks of Sophora japonica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $398/5mg
(+/-)-Puerol B shows inhibitory activity on AGEs formation in vitro.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J. Food Composition and Anal.2022, V 109:104482.
  • Phytother Res.2019, 33(5):1490-1500
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • Pharmacognosy Magazine2017, 13(52):868-874
  • Molecules.2020, 25(9):2081.
  • Braz J Med Biol Res. 2016, 49(7)
  • J Agric Food Chem.2016, 64(35):6783-90
  • Int J Mol Sci.2018, 19(9):E2528
  • Oncol Rep.2019, 41(4):2453-2463
  • J Pharm Biomed Anal.2022, 207:114398.
  • Broussonin B

    Catalog No: CFN97695
    CAS No: 73731-86-9
    Price: $318/10 mg
    Broussonin A

    Catalog No: CFN97694
    CAS No: 73731-87-0
    Price: Inquiry(manager@chemfaces.com)
    Broussonin C

    Catalog No: CFN97690
    CAS No: 76045-49-3
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN98607
    CAS No: 376362-03-7
    Price: Inquiry(manager@chemfaces.com)

    Catalog No: CFN97846
    CAS No: 117614-84-3
    Price: Inquiry(manager@chemfaces.com)
    Puerol A

    Catalog No: CFN96269
    CAS No: 152784-32-2
    Price: Inquiry(manager@chemfaces.com)
    (+)-Puerol B 2''-O-glucoside

    Catalog No: CFN97602
    CAS No: 868409-19-2
    Price: $318/10mg
    Puerol B

    Catalog No: CFN95155
    CAS No: 112343-17-6
    Price: $398/5mg
    Specioside B

    Catalog No: CFN95165
    CAS No: 126589-95-5
    Price: $368/5mg
    Pueroside A

    Catalog No: CFN95177
    CAS No: 100692-52-2
    Price: $318/5mg
    Arch Pharm Res. 2010 Oct;33(10):1651-4.
    Phenolic compounds from Pueraria lobata protect PC12 cells against Aβ-induced toxicity.[Pubmed: 21052940 ]

    Bioassay-guided fractionation of the EtOAc-soluble extract of Pueraria lobata based on the inhibition of Aβ-induced toxicity in PC12 cells resulted in the isolation of four known active compounds, genistein (8), biochanin A (9), sissotrin (10), and Puerol B (11). Of these, genistein (8) and biochanin A (9) exhibited potent neuroprotective effects with ED(50) values of 33.7 and 27.8 μM, respectively. In addition, a new coumestan, 2-(α,α-dimethylallyl)coumestrol (1) was isolated and characterized, but proved to be inactive, as were additional seven known compounds. The structure of new compound 1 was determined using spectroscopic techniques.
    Arch Pharm Res. 2006 Oct;29(10):821-5.
    Constituents of the roots of Pueraria lobata inhibit formation of advanced glycation end products (AGEs).[Pubmed: 17121174 ]

    Two isoflavone C-glucosides, puerarin (1) and PG-3 (2), a but-2-enolide, (+/-)-Puerol B (3), two isoflavone O-glucosides, daidzin (4) and genistin (5), and three pterocarpans, (-)-medicarpin (6), (-)-glycinol (7) and (-)-tuberosin (8), were isolated from a MeOH extract of the roots of Pueraria lobata, using an in vitro bioassay based on the inhibition of the formation of advanced glycation end products (AGEs) to monitor chromatographic fractionation. The structures of 1-8 were determined by spectroscopic data interpretation, particularly by 1D- and 2D-NMR studies, and by comparison of these data with values in the literature. All of the isolates (1-8) were evaluated for their inhibitory activity on AGEs formation in vitro.
    Of these, puerarin (1), PG-3 (2), and (+/-)-Puerol B (3) exhibited more potent inhibitory activity than the positive control aminoguanidine.
    Dactylorhin A

    Catalog No: CFN95032
    CAS No: 256459-34-4
    Price: $238/20mg
    Polygalin C

    Catalog No: CFN95118
    CAS No: 934768-05-5
    Price: $288/5mg

    Catalog No: CFN95245
    CAS No: 866347-36-6
    Price: $318/5mg

    Catalog No: CFN95250
    CAS No: 440094-38-2
    Price: $413/5mg

    Catalog No: CFN95292
    CAS No: 73543-87-0
    Price: $318/10mg
    Lathyranoic acid A

    Catalog No: CFN95325
    CAS No: 850560-44-0
    Price: $318/5mg

    Catalog No: CFN95356
    CAS No: 102582-69-4
    Price: $318/5mg

    Catalog No: CFN95388
    CAS No: 70561-31-8
    Price: $318/10mg
    Tortoside B (Manglieside E)

    Catalog No: CFN95390
    CAS No: 190655-17-5
    Price: $413/5mg
    Oxytroflavoside E

    Catalog No: CFN95464
    CAS No: 1391144-84-5
    Price: $318/5mg