Rosmanol
Catalog No: CFN93024
Rosmanol has antioxidant activity, it can activate the antioxidant response element, it also has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol exhibits significant cytotoxicity towards the neuroblastoma cells, it potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells.Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways.
Rosmarinic acid
Catalog No: CFN99103
Rosmarinic acid has antiviral, antibacterial, antiinflammatory, neuroprotective, anticancer, anti-lipid peroxidative, apoptotic,and antioxidant activities. It is used for food preservation, and to treat peptic ulcers, arthritis, cataract, cancer, rheumatoid arthritis, bronchial asthma, and several human neurodegenerative diseases caused by oxidative stress. Rosmarinic acid has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling. It inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
Rosmarinyl glucoside
Catalog No: CFN95297
Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus.
The scientists found a solution to make Rosmarinic acid available for skin care products. They used glycosylation to convert Rosmarinic acid into Rosmarinyl Glucoside, which is bioavailable, water-soluble and stable in formulations. After penetration trough skin barriers Rosmarinyl Glucoside disintegrates back into Rosmarinic acid. Its biologically active in cells with anti-ageing properties - protecting collagen and hyaluronic acid from destruction by inhibiting enzymes (collagen-destroying enzyme and hyaluronidase). Protects against the degradation of the cellular matrix and captures free-radicals.
A healing herb and one of the most well-known polyphenols for skincare, Rosmarinyl Glucoside guards skin’s extracellular matrix to maintain collagen and keep skin firm, strong and resilient. Its antioxidant activity captures the free radicals that damage skin and inhibit the breakdown of the hyaluronic acid that keeps skin hydrated, plumped, and refreshed.
