Hot Products

Reticuline
Catalog No: CFN98767

Reticuline is a key compound in the biosynthetic pathway for isoquinoline alkaloids in plants, which include morphine, codeine and berberine. Reticuline possesses potent central nervous system depressant action, it (50-100 mg/kg i.p.) can produce alteration of behaviour pattern, prolongation of pentobarbital-induced sleep, reduction in motor coordination and D-amphetamine-induced hypermotility and suppression of the conditioned avoidance response. (S)-Reticuline can elicit vasorelaxation probably due to the blockade of the L-type voltage-dependent Ca(2+) current in rat aorta, the effect may contribute to the potential cardioprotective efficacy of (S)-reticuline.

Retinoic acid
Catalog No: CFN90026

Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. It also helps repair Smad3/TGF-β1-induced lung damage in hyperoxic mice.

Retronecine
Catalog No: CFN00322

Retronecine acts as the better competitor for the competitive inhibition of antibodies to Retronecine. Retronecine can be metabolized to form DHP by rat liver microsomal enzymes and interacts with DNA to produce DHP-DNA adducts and Retronecine N-oxide undergoes the biotransformation to the parent compound, Retronecine.

Retrorsine
Catalog No: CFN00407

Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells.OCT1 mediates the liver-specific uptake of Retrorsine, and plays an important role in Retrorsine-induced hepatotoxicity together with CYP3A4. Consequently, the OCT1 inhibitors could be applied to protect the liver from the toxicity of Retrorsine.

Retusin
Catalog No: CFN89520

Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well as efficient inhibition of cellular melanogenesis.

Retusine
Catalog No: CFN00411

Retusine has edema inhibition capacity, could be related to a reduction of the prostaglandin production. Retusine shows activity against the Gram-positive bacteria C. diphtheria and S. aureus.

Reutericyclin
Catalog No: CFN00135

Reutericyclin is a unique antimicrobial tetramic acid produced by some strains of Lactobacillus reuteri, dissipation of the membrane potential by active Reutericyclins correlated with inhibition of macromolecular synthesis in cells. Reutericyclin and nisin exhibit divergent effects on heat- and pressure-induced spore inactivation and membrane fluidity. All reutericyclins can inhibit the growth of clinical isolates of drug-resistant Staphylococcus aureus, which exemplify the prospect of developing reutericyclins as new topical antibiotics.

Reynosin
Catalog No: CFN98344

Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reciprocal up-regulation of E6-associated protein and down-regulation of α-synuclein protein expression. Reynosin exhibits a dose-dependent inhibition on CINC-1 induction in LPS-stimulated NRK-52E cells, where 50% of inhibitory effect was shown at the concentration of about 1 microM. Reynosin also has strong anti-mycobactericidal activity, with a minimal bactericidal concentration (MBC) of 128ug/mL against the H37Rv, 366-2009 and 104-2010 Mtb strains and a minimal inhibitory concentration (MIC) of 64, 64, 128, 128 and 128ug/mL against the H37Rv, 104-2010, 63-2009, 366-2009 and 430-2010 Mtb strains, respectively.

Reynoutrin
Catalog No: CFN96236

Reynoutrin has antioxidant activity.

Rhamnazin
Catalog No: CFN70409

Rhamnazin, a novel inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy, it attenuates inflammation and inhibits alkali burn-induced corneal neovascularization in rats. Rhamnazin has anti-oxidative, and anti-inflammatry activities, it also shows apoptogenic activity via mitochondrial pathway and associated with activation of caspase-9 and -3.