Matrine
Catalog No: CFN98835
Matrine, a novel autophagy inhibitor, possesses anti-inflammation, immunosuppression, anti-fibrotic and anticancer activities, it could inhibit cell proliferation and induce apoptosis of SGC-7901 cells in vitro by up-regulating Fas/FasL expression and activating caspase-3 enzyme. Matrine can be a potential candidate to fight against Candida-related infections by regulating yeast-to-hypha transition.
Medicarpin
Catalog No: CFN98411
Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERβ, promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in addition, given its excellent oral bioavailability, it can be potential osteogenic agent. Medicarpin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway. Medicarpin also has antifungal activity.
Melatonin
Catalog No: CFN90037
Melatonin, a hormone produced in the brain, is a potent melatonin receptor activator, and possesses important anti-cancer, antioxidative and anti-inflammatory properties,
it can reduce lead toxicity in vivo and in vitro. Melatonin may be useful as a pharmacological agent to protect against hepatic metabolic diseases due to its ability to regulate expression of miR-23a.
