Hot Products

Linalyl acetate
Catalog No: CFN70038

Linalyl acetate, the main component of lavender oil is commonly used as a fragrance chemical in scented products. Linalyl acetate relaxes vascular smooth muscle through dephosphorylaton of myosin light chain. Linalyl acetate has genotoxicity.

Linarin
Catalog No: CFN98738

Linarin possesses analgesic, antipyretic, anti-acetylcholinesterase, hepatoprotective ,anti-inflammatory and neuroprotective activities, it prevents Aβ(25-35)-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3β and up-regulates Bcl-2. Linarin can protect osteoblasts against hydrogen peroxide-induced osteoblastic dysfunction and may exert anti-resorptive actions, at least in part, via the reduction of RANKL and oxidative damage; it also can treat postmenopausal osteoporosis,it induces the osteogenic differentiation and mineralization of MC3T3-E1 osteoblastic cells by activating the BMP-2/RUNX2 pathway through PKA signalingin vitroand protected against OVX-induced bone lossin vivo.

Linaroside
Catalog No: CFN91714

Linaroside exhibited 30% inhibition for antimycobacterial activity against Mycobacterium tuberculosis, strain H(37)Rv at 6.25 microg mL(-1) concentration. The nematicidal activity of Linaroside against the root-knot nematode M. incognita, showed 90% mortality at 1.0% concentration.

Linderalactone
Catalog No: CFN99761

Linderalactone shows hepatoprotective activity against H2O2-induced oxidative damages on HepG2 cells with the EC(50) value of 98.0 microM. It shows significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, the IC50 is 8.48 microg/mL.

Linderane
Catalog No: CFN98175

Linderane is a mechanism-based inactivator of CYP2C9.

Linderone
Catalog No: CFN99837

Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.

Linezolid
Catalog No: CFN60414

Linoleic acid
Catalog No: CFN93168

Essential fatty acid. Prostaglandin precursor.Linoleic acid could be involved in the inflammatory response through stimulation of the neutrophil chemokine, IL-8.

Linolenic acid
Catalog No: CFN70110

Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women.Alpha-linolenic acid (ALA) reduces cardiovascular disease (CVD) risk, possibly by favorably changing vascular inflammation and endothelial dysfunction. Conjugated linolenic acid shows possible chemopreventive activity in the early phase of colon tumorigenesis through modulation of cryptal cell proliferation activity and/or apoptosis.

Lipoic acid
Catalog No: CFN99192

Alpha-lipoic acid has become a common ingredient in multivitamin formulas, anti-aging supplements, and even pet food, it is well-defined as a therapy for preventing diabetic polyneuropathies, and scavenges free radicals, chelates metals, and restores intracellular glutathione levels which otherwise decline with age. Alpha-lipoic acid has therapeutic effects on joint inflammation and erosion in an animal model via NF-kappa B down regulation, it inhibits TNF-alpha induced NF-kappa B activation through blocking of MEKK1-MKK4-IKK signaling cascades. Lipoic acid is a novel treatment for Alzheimer's disease and related dementias.