Hot Products

Lycopsamine N-oxide
Catalog No: CFN00463

Lycorenine
Catalog No: CFN90363

Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and produce bradycardia by modifying vagal activity. The development of tachyphylaxis to the vasodepressor action of lycorenine is ascribed to maintenance of its alpha-adrenergic blocking action.

Lycorine
Catalog No: CFN90263

Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.Lycorine has antiviral, and anti-cancer effects, the mechanisms of Lycorine on the multiple myeloma cell line ARH-77 are associated with G1 phase cell cycle arrest, mitochondrial dysfunction, reactive oxygen species (ROS) generation, ATP depletion, and DNA damage.

Lycorine chloride
Catalog No: CFN99730

Lycorine chloride( Lycorine hydrochloride) is a VE-cadherin inhibitor with the IC50 of 1.2μM in Hey1B cell. It selectively inhibited ovarian cancer cell proliferation and neovascularization and is a potential drug candidate for anti-ovarian cancer therapy.

Lyoniside
Catalog No: CFN98451

Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compounds potential anti-leishmanial candidates. The synergistic action of lyoniside and triterpene acids was demonstrated in inhibitory effect exerted on germination and growth of Pinus sylvestris.

Lysicamine
Catalog No: CFN93254

Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the minimum inhibitory concentrations of the pour component (Streptococcus mutans, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans.) is less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation is 0.2mg/ml for both IL-8 and IL-6. Lysicamine has antileishmanial activity. It can significantly inhibit the proliferation of melanoma cells, it has antioxidative activity and chemopreventive activity in skin melanoma cells.

Lysionotin
Catalog No: CFN99787

Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities. It is an efficient inhibitor of α-toxin expression and shows significant protection against S. aureus in vitro and in vivo.

Maackiain
Catalog No: CFN99746

Maackiain is an antimicrobial compound (phytoalexins), it has anticancer effects, it induces apoptosis and growth suppression. Maackiain also shows strong larvicidal activity (LC50 = 21.95 ± 1.34 ug/mL).

Macamide B
Catalog No: CFN90843

Reference standards.

Maclurin
Catalog No: CFN98836

Maclurin can effectively protect against mesenchymal stem cells (MSCs) oxidative damage induced by hydroxyl radical (OH) at 62.1-310.5 uM, the protective and antioxidant effects of maclurin can be primarily attributed to ortho-dihydroxyl groups, and ultimately to the relative stability of the ortho-benzoquinone form.Maclurin has anti-metastatic effect, the mechanism is by anti-oxidative activity and inhibition of Src/FAK-ERK-β-catenin signaling pathway.