Hot Products

Macrocarpal A
Catalog No: CFN99413

Macrocarpal A is the key component that stimulates the synthesis of ceramide in the stratum corneum. Macrocarpal A has cytotoxic, and antibacterial activities.

Macrocarpal B
Catalog No: CFN99472

The intestinal absorption of M-A, Macrocarpal B, and Cy-C was passive diffusion as the dominating process and Cy-C was partly ATP-dependent.

Macrocarpal C
Catalog No: CFN99469

Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifungal action of macrocarpal C was associated with increases of membrane permeability, intracellular ROS and DNA fragmentation.

Macrocarpal H
Catalog No: CFN99841

Macrocarpal H has anti-glucosyltransferase, and anti-bacterial activities.

Macrocarpal I
Catalog No: CFN99842

Macrocarpal I has anti-glucosyltransferase, and anti-bacterial activities.

Madecassic acid
Catalog No: CFN99914

Madecassic acid has anti-diabetic, anti- tumor, wound-healing, and anti-inflammatory properties, it can improve glycemic control and hemostatic imbalance, lower lipid accumulation, and attenuate oxidative and inflammatory stress in diabetic mice. It can protect against hypoxia-induced oxidative stress in retinal microvascular endothelial cells via ROS-mediated endoplasmic reticulum stress. It inhibited the esspession of NOS, COX-2, TNF-alpha, IL-1beta, IL-6, and the downregulation of NF-kappaB activation.

Madecassoside
Catalog No: CFN99913

Madecassoside is a mechanism-based inhibitor of CYP2C19 and CYP3A4, which has antioxidant, anti-inflammatory, anti-apoptosis, wound-healing, and neuroprotective activities, It may have cardioprotective effects in LPS-mediated through inhibition of ERK, p38, and NF-κB activity, it inhibited the pro-inflammatory mediators, including COX-2 expression, PGE2 production, TNF-αand IL-6 levels and the up-regulation anti-inflammatory molecule IL-10.

Magnaldehyde B
Catalog No: CFN95075

Magnaldehyde B is a natural lipase inhibitor(IC50= 96.96 uM). Magnaldehyde B can inhibit the proliferation of tumor cells, and might be an anti-tumoric agent.

Magnaldehyde D
Catalog No: CFN96172

Magnaldehyde D is a natural product from Magnolia officinalis.

Magnesium Lithospermate B
Catalog No: CFN90390

Magnesium lithospermate B is a naturally occurring, new generation antioxidant that activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from ischemic injury through specific inhibition of TAB1-p38 apoptosis signaling. Magnesium lithospermate B possesses inhibitory activity on Na+,K+-ATPase, it provides anti-ischemic neuroprotection in gerbilssubjected to focal ischemia and reperfusion. Magnesium lithospermate B has potent antifibrotic effect in intraperitoneal thioacetamide (TAA)-treated cirrhotic rats, and inhibits fibrogenic responses in hepatic stellate cells (HSCs). It has depressor action on blood pressure in spontaneously hypertensive rats.Magnesium lithospermate B also has anti-wrinkle and anti-aging effects on skin.