Hot Products

Licochalcone C
Catalog No: CFN99577

Licochalcone C has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activities; it shows inhibition of bacterial growth and cellular respiration. Licochalcone C exhibits inhibitory activity with cytotoxicity in a rat basophilic leukemia cell line, RBL-2H3. It induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells, it may be a potential adjuvant therapeutic agent for bladder cancer.

Licochalcone D
Catalog No: CFN93186

Licochalcone D has anti-inflammatory, and anti-allergic activities, it shows suppression ability of nitric oxide (NO) production, it also suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. It may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion.

Licochalcone E
Catalog No: CFN93297

Licochalcone E is a potential LXRβ agonist, which has chemopreventive, cytotoxic, anti-inflammatory, antimicrobial, antidiabetic effects; it increases the levels of PPARγ expression, at least in part, via the stimulation of Akt signals and functions as a PPARγ partial agonist. Licochalcone E may be used for the treatment of hepatotoxicity, and primarily exhibits its protective role through a PPARγ/NF-κB-mediated pathway. Licochalcone E is also a potential activator of the Nrf2/ARE-dependent pathway and is therapeutically relevant not only to oxidative-stress-related neurodegeneration but also inflammatory responses of microglial cells both in vitro and in vivo.

Licoflavanone
Catalog No: CFN95213

Licoflavanone exhibits antioxidant and anti-inflammatory activities,it markedly decreases pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels.

Licoflavone A
Catalog No: CFN93265

Reference standards.

Licoflavone C
Catalog No: CFN92289

Licoflavone C has cytotoxic, and antioxidative effects, it has protective effect toward the chromosome damage induced by DAU or MMC in cultured human peripheral lymphocytes. Licoflavone C exhibits a dose-dependent antagonistic activity at concentrations up to 10−4 M, but stimulates β-galactosidase expression at higher concentrations resulting in a U-shaped-like dose-response curve.

Licoflavonol
Catalog No: CFN96515

Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC.

Licoisoflavanone
Catalog No: CFN96544

Licoisoflavanone is a natural product from Licorice.

Licoisoflavone A
Catalog No: CFN90816

Licoisoflavone A is a potential MRP inhibitor, it shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro.

Licoisoflavone B
Catalog No: CFN96405

Licoisoflavone B is an inhibitor of germ tube growth in the arbuscular mycorrhizal (AM) fungus Gigaspora margarita, it can strongly inhibit germ tube growth at 0.63 ug/disc, and it can completely inhibit hyphal branching induced by a lupin strigolactone, orobanchyl acetate, in G. margarita at 0.16 ug/disc. Licoisoflavone B exhibits inhibitory activity against the growth of Helicobacter pylori in vitro, it also shows anti-H. pylori activity against a clarithromycin (CLAR) and amoxicillin (AMOX)-resistant strain.Licoisoflavone B exhibits antimutagenic activity against carcinogenic N-methyl-N-nitrosourea (MNU), it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.