Hot Products

Glabrone
Catalog No: CFN93041

Glabrone shows antiviral activity against influenza virus. It also exhibits significant PPAR-gamma ligand-binding activity.

Glaucin B
Catalog No: CFN99256

Glaucin B is a new bitter limonoid.

Glaucine
Catalog No: CFN90408

Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IκBα and NF-κB activities.

Glaucocalyxin A
Catalog No: CFN90207

Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand. Glaucocalyxin A has regulation of microglia activity, can attenuate lipopolysaccharide -stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathways.Glaucocalyxin A may become a potential anti-fibrotic agent in Idiopathic pulmonary fibrosis (IPF) management, it can effectively ameliorate pulmonary fibrosis through the antagonism of leukocyte infiltration and proinflammatory cytokine production.

Glaucoside A
Catalog No: CFN95299

Anticancer. Glaucoside A was evaluated against the HT-29 and HCT 116 human colon cancer cell lines.

Glaucoside C
Catalog No: CFN95300

Anticancer. Glaucoside C was evaluated against the HT-29 and HCT 116 human colon cancer cell lines.

Glepidotin B
Catalog No: CFN97977

Reference standards.

Glibenclamide
Catalog No: CFN80103

Glibenclamide is a known blocker of vascular ATP-sensitive K+ channels (KATP), used in the treatment of type 2 diabetes.Glibenclamide increases the risk for hypoglycemia by increasing insulin secretion, it plays a paradoxical protective role to protect against severe hypoglycemia-induced fatal cardiac arrhythmias; it also reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.

Glicoricone
Catalog No: CFN95063

Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.

Gliotoxin
Catalog No: CFN93993

Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. Gliotoxin targets nuclear NOTCH2 in human solid tumor derived cell lines in vitro and inhibits melanoma growth in xenograft mouse model. Gliotoxin exhibits very strong anti-tuberculosis activity towards Mycobacterium tuberculosis with the the prominent MIC50 value of <0.03 uM. Gliotoxin also suppresses macrophage immune function by subverting phosphatidylinositol 3,4,5-trisphosphate homeostasis.