Hot Products

Gnetol
Catalog No: CFN92425

Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells, it has a strong inhibitory effect on murine tyrosinase activity. Gnetol is active in the inhibition of arachidonic acid (AA)-induced platelet aggregation.Gnetol has the IC(50) value of 1.3 uM towards butyrylcholinesterase and shows a reversible and competitive inhibition in the kinetic study.

Gnetulin
Catalog No: CFN92444

Standard reference

Goitrin
Catalog No: CFN90623

Goitrin is a potent antithyroid compound, it is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase,leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine. Goitrin is responsible for the induction of glutathione S-transferases.

Gomisin A
Catalog No: CFN98990

Gomisin A has anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties, it induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. Gomisin A inhibits COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation.

Gomisin D
Catalog No: CFN90122

Gomisin D is a natural product from Schizandra chinensis.

Gomisin E
Catalog No: CFN96725

Gomisin E is a natural product from Schizandra chinensis.

Gomisin F
Catalog No: CFN92719

Standard reference

Gomisin G
Catalog No: CFN90123

Gomisin G is a drug candidate for treatment of cardiovascular disease, and it is a good substrate of CYP2C9, and can be easily affected by the inhibitors of CYP2C9. Gomisin G exhibits anti-tumor activities, it exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.

Gomisin H
Catalog No: CFN94008

Gomisin H is a natural product from Schizandra chinensis.

Gomisin J
Catalog No: CFN90124

Gomisin J is a good substrate of cytochrome P450 3A4(CYP3A4), it has vasodilatory, anti-inflammatory, anti-diabetes, anti-oxidant, and anti-cancer effects, it also has preventive effects on angiotensin II-induced hypertension via an increased nitric oxide bioavailability. Gomisin J has potential benefits in treating nonalcoholic fatty liver disease, it can suppress lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecule. Halogenated gomisin J is a potent inhibitor of the cytopathic effects of human immunodeficiency virus type 1 (HIV-1) on MT-4 human T cells (50% effective dose, 0.1 to 0.5 microM).