Hot Products

Corylifol A
Catalog No: CFN92226

Corylifol A is a naturally occurring potent inhibitor of hCE2 and UDP-glucuronosyltransferase 1A1 (UGT1A1); it could be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A has antiinflammatory activity, it shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uΜ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells.

Corylifol B
Catalog No: CFN92227

Reference standards.

Corylifol C
Catalog No: CFN92228

Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6)  μg/ml, respectively).

Corylin
Catalog No: CFN98902

Corylin has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties, it may stimulate bone formation or have potential activity against osteoporosis. Corylin shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells.

Corymboside
Catalog No: CFN95292

Anti-inflammatory.
Corymboside has been detected, but not quantified in, cereals and cereal products and wheats. This could make corymboside a potential biomarker for the consumption of these foods.

Corymbosin
Catalog No: CFN96498

Corymbosin shows significant antiviral activity.

Corynantheine
Catalog No: CFN92843

Corynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum).

Corynanthine
Catalog No: CFN70375

Corynanthine is an alpha 1-adrenoceptor and alpha 2-adrenoceptor antagonist. Corynanthine inhibits, while idazoxan potentiates, cardiotoxic effects of ouabain. It modulates DNA synthesis in mitogen-stimulated human lymphocytes.

Corynoxeine
Catalog No: CFN98154

Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.

Corynoxine
Catalog No: CFN90218

Corynoxine is a natural autophagy enhancer, promotes the clearance of Alpha-synuclein via Akt/mTOR pathway, it can significantly inhibit the oxidative stress of PC12 cells.