Hot Products

Cycloartenyl ferulate
Catalog No: CFN91779

Cycloartenyl ferulate possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities.

Cycloastragenol
Catalog No: CFN99538

Cycloastragenol has been shown to extend T cell proliferation by increasing telomarase activity showing that it may also help delay the onset of cellular aging; it is an extraordinary wound healing agent; it inhibits the apoptosis of PC12 induced by 6-OHDA, may be as potential neuroprotective agents in the treatment of Parkinson's disease. Cycloastragenol and astragaloside IV can suppress ROS-associated ER stress and then inhibit TXNIP/NLRP3 inflammasome activation with regulation of AMPK activity, and thereby ameliorate endothelial dysfunction by inhibiting inflammation and reducing cell apoptosis. Cycloastragenol and astragaloside IV have been shown to improve the proliferative response of CD8+ T lymphocytes from HIV-infected patients by upregulating telomerase activity, they also may exert their cellular effects through the activation of the Src/MEK/ERK pathway.

Cyclocommunol
Catalog No: CFN92418

Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation.

Cyclocurcumin
Catalog No: CFN95103

Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It may have a therapeutic potential as a novel antivasoconstrictive natural product. Cyclocurcumin offers higher neuronal protection than curcumin, they both reduced the level of ROS caused by MPP+ treatment.

Cycloeucalenol
Catalog No: CFN98701

Cycloeucalenol produces mild cardiotonic effects. Cycloeucalenol and its regio-isomer were present in a ratio of 1.04:1, a dose-dependent decrease in cell viability was observed.

Cyclomorusin
Catalog No: CFN97714

Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophils. Cyclomorusin , neocyclomorusin and kuwanon C inhibited cholinesterase enzyme in a dose-dependent manner with K(i) values ranging between 3.1 and 37.5 uM and between 1.7 and 19.1 uM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively.

Cyclomulberrin
Catalog No: CFN92417

Cyclomulberrin shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation, it also shows slight but significant antiplatelet effects on the aggregation induced by PAF. Cyclomulberrin enhances cell viability in a dose-dependent manner against sodium nitroprusside-induced cell death in neuroblastoma SH-SY5Y cells. It exhibits potent inhibition of human PLC/PRF/5 and KB cells in-vitro.

Cycloolivil
Catalog No: CFN96185

(+)-Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies.

Cyclopamine
Catalog No: CFN90928

Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay, it can increase levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells. Cyclopamine as a novel, potent inhibitor of human breast cancer proliferation and estrogen responsiveness that could potentially be developed into a promising therapeutic agent for the treatment of breast cancer. Cyclopamine also can suppress the growth of leukemia and lymphoma cells.

Cyclopentadecanone
Catalog No: CFN93169

Used in perfumery (musk odour).