Daphnetin
Catalog No: CFN99952
Daphnetin is a dihydroxycoumarin that is being used in China for the treatment of coagulation disorders, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit antimalarial, anti-rheumatoid arthritis, anti-proliferative, anti-inflammatory and anti-oxidant activities. it is also a chelator and an antioxidant. Daphnetin can enhance immunological functions of B lymphocytes, the expression of IL-12 in B lymphocytes can be up-regulated by daphnetin through natural immunity approach.
Daphnodorin B
Catalog No: CFN92959
Daphnodorin B has antifungal, antimitotic and anti-HIV-1 activity, it induced morphological deformation of P. oryzae mycelia with MMDC values of 73.7 +/- 1.6 microM, it showed moderate activity against microtubule polymerization with IC50 values of 142 +/- 2 microM in vitro, and it moderately active against HIV-1 in vitro. Daphnodorin B shows inhibitory effects of human chymase. Daphnodorin B inhibited tumor growth and metastasis by protecting host immunocyte viability and proliferation potential, and selectively inhibiting tumor cell proliferation.
