Delta3,2-Hydroxylbakuchiol
Catalog No: CFN92803
Delta3,2-Hydroxylbakuchiol, a monoamine transporter inhibitor involved in regulating dopaminergic and noradrenergic neurotransmission and may have represented potential pharmacotherapies for disorders such as Parkinson's disease, depression, and cocaine addiction.
Delta-9-Tetrahydrocannabinol
Catalog No: CFN91898
Delta 9-tetrahydrocannabinol(THC) induces dopamine release in the human striatum, this allows new directions in research on the effects of THC in neuropsychiatric disorders, such as schizophrenia.
THC demonstrates an analgesic effect in patients experiencing cancer pain, it has antiemetic effect in patients receiving cancer chemotherapy. THC shows neuroprotection against ouabain-induced in vivo excitotoxicity, it promotes tumor growth by inhibiting antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway.
Delta-Tocotrienol
Catalog No: CFN96406
Delta-tocotrienol is a potential angiogenic inhibitor, it (2.5-5 microM) can significantly suppress human colorectal adenocarcinoma cells (DLD-1-CM) -induced tube formation, migration, and adhesion on human umbilical vein endothelial cells.It is also a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offering a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects, it protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling.
Demethoxycurcumin
Catalog No: CFN99185
Demethoxycurcumin is a potential additive natural product in combination with chemotherapeutic agents in drug-resistant cancers, which has anti-acanthamoebic, anti-proliferative, antimetastatic, anti-inflammatory, antioxidant activities. It inhibited P-glycoprotein-mediated ATP hydrolysis under concentrations of <1 μM and efficiently inhibited 200 μM verapamil-stimulated ATPase activity.